Nucleocytoplasmic transport: driving and directing transport

Current Biology : CB
C N Cole, C M Hammell

Abstract

Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran. The asymmetric distribution of Ran regulator proteins, RanGAP1 and RCC1, provides the driving force and directionality for nuclear transport.

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