Nucleophilic trifluoromethylthiolation of bromoalkynones with AgSCF3 : C(sp)-SCF3 bond formation towards ynonyl trifluoromethyl sulfides

Organic & Biomolecular Chemistry
Huanfeng JiangWanqing Wu

Abstract

An AgSCF3 mediated nucleophilic trifluoromethylthiolation reaction for C(sp)-SCF3 bond formation is reported. This nucleophilic trifluoromethylthiolation reaction of bromoalkynones afforded various useful ynonyl trifluoromethyl sulfides in high yields. Interestingly, the over-addition of AgSCF3 is avoided in our approach.

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Citations

Mar 13, 2019·Organic & Biomolecular Chemistry·Mei ZhuBaoming Ji

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Methods Mentioned

BETA
NMR

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