Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes

Journal of Virology
Hans Helmut NillerJanos Minarovits

Abstract

Genomic footprints across Rp, Zp, and oriLyt of Epstein-Barr virus (EBV) have been conducted in a panel of latently infected B-cell lines. Close protein-base contacts were found about 360 nucleotides upstream of the Zp initiation site. Gel shifts and transient transfection assays indicated that an Sp1-NF1 locus may serve as a repressive transcriptional element against Zp induction from latent EBV genomes.

References

Jul 1, 1991·Journal of Virology·E A MontalvoA J Levine
May 1, 1991·Journal of Virology·A J SinclairP J Farrell
May 26, 1995·The Journal of Biological Chemistry·H H NillerH Wolf
Jul 1, 1993·Journal of Virology·A SchepersW Hammerschmidt
Aug 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·S ZalaniS Kenney
Nov 14, 1997·Trends in Microbiology·S H SpeckE Flemington
Jan 7, 2000·Journal of Virology·P J JenkinsP J Farrell
Jan 11, 2000·Nucleic Acids Research·E WingenderS Urbach

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Citations

Dec 13, 2002·Journal of Virology·Richard J KrausJanet E Mertz
Mar 19, 2004·Immunology·Yoshifumi NagataIchiro Saito
May 3, 2014·Microbiology and Immunology·Takayuki Murata
Jul 22, 2014·Future Microbiology·Hans Helmut NillerJanos Minarovits
May 29, 2003·The Journal of General Virology·Orlando de JesusPaul J Farrell

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