Nucleotide oligomerization domain 2 (Nod2) is not involved in the pattern recognition of Candida albicans

Clinical and Vaccine Immunology : CVI
Chantal A A Van Der GraafBart Jan Kullberg

Abstract

Nucleotide-binding oligomerization domain 2 (Nod2) pathways are known to interact with Toll-like receptor 2 (TLR2) and TLR4, which are pattern recognition receptors for Candida albicans. We observed that the prevalence of Nod2 polymorphisms was not increased in patients with Candida infections. Candida-induced cytokine production in individuals with Nod2 polymorphisms was unaffected. We conclude that Nod2 is unlikely to play an important role in the recognition of Candida albicans.

References

Aug 30, 2000·Nature·A Aderem, R J Ulevitch
Nov 4, 2000·The Journal of Biological Chemistry·N InoharaG Nuñez
Apr 27, 2002·Immunogenetics·Laura MurilloA Salvador Peña
May 7, 2002·The Journal of Infectious Diseases·Mihai G NeteaBart Jan Kullberg
Jan 16, 2003·The Journal of Biological Chemistry·Stephen E GirardinPhilippe J Sansonetti
Jun 7, 2003·Science·Stephen E GirardinDana J Philpott
Sep 23, 2003·Clinical Chemistry·Orazio PalmieriPaolo Fortina
Oct 18, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L Ostrosky-ZeichnerJ H Rex
Jun 29, 2004·Nature Immunology·Tomohiro WatanabeWarren Strober
Sep 16, 2004·Journal of Clinical Periodontology·M L LaineA J van Winkelhoff
May 10, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mihai G NeteaJos W M Van der Meer
Oct 22, 2005·Infection and Immunity·Chantal A A van der GraafBart Jan Kullberg

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Citations

Dec 15, 2007·Nature Reviews. Microbiology·Mihai G NeteaNeil A R Gow
Dec 14, 2011·Nature Reviews. Microbiology·Neil A R GowMihai G Netea
Sep 27, 2008·Acta Pharmacologica Sinica·Hui-jun ZhangZheng-hong Yuan
Apr 17, 2010·Journal of Dental Research·G WeindlM Schaller
Feb 13, 2010·Trends in Immunology·Linda M RehaumeMathias Chamaillard
May 1, 2009·Microbial Biotechnology·David M AranaJesús Pla
May 23, 2012·Cell Host & Microbe·Nydiaris Hernández-Santos, Sarah L Gaffen
Oct 29, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F L van de VeerdonkM G Netea
Oct 4, 2012·Expert Review of Anti-infective Therapy·Corine E DelsingMihai G Netea
Mar 3, 2017·PLoS Pathogens·Ziad Al NabhaniFrederick Barreau
May 28, 2009·The American Journal of Gastroenterology·Annie Standaert-VitseJean-Frédéric Colombel
Feb 27, 2019·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Philip KienzlAdelheid Elbe-Bürger
Jun 5, 2016·The Journal of Immunology : Official Journal of the American Association of Immunologists·Emmanuel C PatinSelinda J Orr
Mar 19, 2020·Frontiers in Cellular and Infection Microbiology·Richard M Merkhofer, Bruce S Klein
Jul 8, 2018·Nature Communications·Mark S GresnigtFrank L van de Veerdonk

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