PMID: 6159590Oct 10, 1980Paper

Nucleotide sequence analysis of precursor 5S RNA from Bacillus licheniformis

Nucleic Acids Research
W J StiekemaR J Planta

Abstract

The complete nucleotide sequences of the various precursor 5S RNA species occurring in Bacillus licheniformis have been elucidated. The B. licheniformis precursors contain a 5'-precursor-specific segment of 95 nucleotides which is four times as long as the corresponding segment of the p5S RNAs from the closely related strains B. subtilis (Sogin, M.L., Pace, N.R., Rosenberg, M., Weissman, S.M. (1976) J. Biol. Chem. 251, 3480-3488) and Bacillus Q (Stiekema, W.J., Raué, H.A., Planta, R.J. (1980) Nucl. Ac. Res. 8, 2193-2211). However, fourteen of the sixteen nucleotides at the 5'-end are identical in the precursors from all three strains. These conserved nucleotides can form a stem and loop structure which is likely to play an important role in the biosynthesis of 5S RNA. Extension secondary and tertiary structure is present in the 5'-precursor-specific segment as concluded from the results of digestion with RNAase T1 both of the isolated segment and the intact precursors. No sequence homology exists between the 3'-precursor-specific segments of the B. licheniformis precursors and those of the other two strains except for a stretch of U residues at the 3-terminus. This stretch of U residues is not immediately preceded by a hairpin ...Continue Reading

References

Jul 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·B MeyhackN R Pace
Jan 1, 1978·Annual Review of Biochemistry·S Adhya, M Gottesman
Nov 14, 1977·Molecular & General Genetics : MGG·H A RauéR J Planta
Aug 7, 1975·Nature·G E Fox, C R Woese
May 24, 1980·Nucleic Acids Research·W J StiekemaR J Planta

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Citations

Oct 11, 1983·Nucleic Acids Research·K LoughneyJ E Dahlberg

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