PMID: 639801Mar 15, 1978Paper

Nucleotide sequence at the 5' extremity of tobacco-mosaic-virus RNA. 2. The coding region (nucleotides 69-236)

European Journal of Biochemistry
G JonardP Gerlinger

Abstract

In the preceding paper it was shown that the first A-U-G codon in tobacco mosaic virus RNA is separated from the 5' terminus by a sequence of 68 nucleotides devoid of internal guanosine residues. In this paper we present the sequence of 165 residues immediately following the first potential initiation codon. The characterized sequence contains four nonsense codons but none are in phase with the prospective initiation codon. Several lines of evidence, including direct characterization of the portion of the RNA molecule which binds to and is protected by the ribosome in the course of initiation, all support the idea that the A-U-G at position 69-71 is a functional initiation signal for viral protein synthesis.

References

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Mar 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·G W BothA J Shatkin
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Jan 1, 1963·Advances in Protein Chemistry·D L CASPAR

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Citations

Jul 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·J P BriandH Guilley
Oct 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·P GoeletJ Karn
Jan 11, 1980·Nucleic Acids Research·R GranthamA Pavé
Jul 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·W Filipowicz, A L Haenni
Feb 17, 2015·Virus Research·Tetsuya ChujoMasayuki Ishikawa

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