PMID: 9435124Jan 22, 1998Paper

Nucleotide variation in the cytidine triphosphate synthetase gene of Giardia duodenalis

The Journal of Eukaryotic Microbiology
A SwarbrickT S Stewart

Abstract

The cytidine triphosphate synthetase genes from three diverse strains of Giardia duodenalis have been sequenced and found to vary significantly from one another. The isolates were chosen as representatives of three demes as determined by several criteria including divergence in the rDNA repeat unit. Inserts in the genes and protein are conserved in length but are the most divergent regions among the three sequences examined. Variation in the rest of the gene occurs primarily in the third base position resulting in many silent mutations. One of the isolates (1709) was found to contain two genes with high sequence homology.

References

Feb 1, 1976·Experimental Parasitology·E A Meyer
Dec 1, 1991·Molecular & General Genetics : MGG·O Ozier-KalogeropoulosF Lacroute
Apr 1, 1989·International Journal for Parasitology·R H AndrewsB P Meloni
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·R E PhillipsR W Shepherd
May 1, 1994·The Journal of Eukaryotic Microbiology·J A Upcroft, P Upcroft
Aug 1, 1994·International Journal for Parasitology·B M Jiménez, W J O'Sullivan
Feb 1, 1996·Molecular and Biochemical Parasitology·J A UpcroftP Upcroft

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Citations

Jan 9, 2001·Clinical Microbiology Reviews·P Upcroft, J A Upcroft

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