PMID: 15229357Jul 2, 2004Paper

Number of secretory vesicles in growth hormone cells of the pituitary remains unchanged after secretion

Experimental Biology and Medicine
Jin-Sook LeeLloyd L Anderson

Abstract

Immunogold-labeled transmission electron microscopy (TEM) was used to determine the total number of secretory vesicles in resting and in growth hormone (GH)-stimulated porcine pituitary cells. We identified three categories of vesicles: filled, empty, and partly empty. Resting GH cells contained more than twice as many filled vesicles than did the stimulated ones. Stimulated cells, however, contained nearly twice as many empty vesicles and 2.5 times more partly empty vesicles than did resting cells. Secretory vesicles in GH cells further revealed the localization of GH only in electron-dense vesicles in both resting and stimulated cells. The total number of secretory vesicles did not change after secretion. These results are consistent with a mechanism that, after stimulation of secretion, vesicles transiently dock and fuse at the fusion pore to release vesicular contents.

References

Feb 1, 1976·The Journal of Endocrinology·L L AndersonC R Bohnker
Apr 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·L J Breckenridge, W Almers
Nov 1, 1986·Proceedings of the Society for Experimental Biology and Medicine·J R MolinaL L Anderson
Mar 1, 1967·The Journal of Endocrinology·J J Ford, L L Anderson
Apr 1, 1983·Proceedings of the Society for Experimental Biology and Medicine·J KlindtL L Anderson
Jul 1, 1996·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·J E DriskoG J Hickey
Jan 7, 1997·Proceedings of the National Academy of Sciences of the United States of America·S W SchneiderB P Jena
May 1, 1997·Cell Biology International·B P Jena
Dec 16, 1997·Proceedings of the National Academy of Sciences of the United States of America·B P JenaK C Sritharan
Aug 24, 1999·Cell Biology International·E H JeongB P Jena
Dec 22, 1999·Biochemical and Biophysical Research Communications·K ValentijnJ D Jamieson
Jan 10, 2002·Cell Biology International·Sang-Joon ChoBhanu P Jena
Jan 10, 2002·Cell Biology International·Sang-Joon ChoBhanu P Jena
Jan 29, 2002·Animal Reproduction Science·H S SunC K Tuggle
Mar 28, 2002·Proceedings of the National Academy of Sciences of the United States of America·Sang-Joon ChoBhanu P Jena
Nov 5, 2002·Biophysical Journal·Sang-Joon ChoBhanu P Jena
Nov 20, 2002·Annals of the New York Academy of Sciences·S-J ChoB P Jena
Dec 12, 2002·The Journal of Endocrinology·A Glavaski-JoksimovicS Jeftinija
Jan 23, 2003·Proceedings of the National Academy of Sciences of the United States of America·Justin W TaraskaWolfhard Almers
Jan 28, 2003·Biophysical Journal·Bhanu P JenaRania Abu-Hamdah
Jan 30, 2003·The Journal of Endocrinology·B P Jena
Jul 8, 2003·Neuroendocrinology·Aleksandra Glavaski-JoksimovicSrdija Jeftinija
Aug 29, 2003·Biophysical Journal·Aleksandar JeremicBhanu P Jena
Feb 5, 2004·Cell Biology International·Rania Abu-HamdahBhanu P Jena
Feb 5, 2004·Cell Biology International·Aleksandar JeremicBhanu P Jena

❮ Previous
Next ❯

Citations

Oct 19, 2004·Histochemistry and Cell Biology·Jin-Sook LeeLloyd L Anderson
Jun 3, 2010·Angewandte Chemie·Siowling SohBartosz A Grzybowski
Feb 22, 2012·Cell Biology International Reports·Dennis G DrescherMarian J Drescher
Feb 9, 2012·Experimental Biology and Medicine·Lloyd L Anderson, Colin G Scanes
Apr 28, 2005·Experimental Biology and Medicine·Bhanu P Jena
Mar 28, 2008·Journal of Cellular and Molecular Medicine·A Jeremic
Jun 2, 2005·Domestic Animal Endocrinology·L L AndersonA Glavaski-Joksimovic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved