PMID: 6172766Jan 1, 1982Paper

Numerical frequency of epithelial abnormalities, particularly microkeratocysts, in the developing human oral mucosa

Oral Surgery, Oral Medicine, and Oral Pathology
M C Moreillon, H E Schroeder

Abstract

Clinically manifest gingival and median palatal cysts in the adult are relatively rare lesions. The present study using Epon-embedded material and serial paraffin sections of fifty-five human heads, approximately 8 to 22 weeks of fetal age, demonstrated that (1) dental lamina-derived microkeratocysts develop and increase in number from the twelfth to the twenty-second week, with a maximum of 190 cysts per fetus; (2) midpalatal microkeratocysts reach a peak number of below 20 per fetus at week 14 and do not become more numerous with time. In addition, morphologic findings offer evidence of fetal cyst development through differentiation phenomena and reconfirm the discharge mechanism responsible for cyst disappearance. It appears that cyst development through epithelial differentiation is an essential step if it is to be at all possible for discharge to occur. Most microcysts of the alveolar crest and the midpalatal region are apparently discharged shortly after birth, therefore, the respective cysts in the adult are rare.

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Citations

Feb 1, 1991·International Journal of Oral and Maxillofacial Surgery·M D DeGould, J S Goldberg
Jun 1, 1994·International Journal of Paediatric Dentistry·A FlinckI Axelsson
Nov 7, 1999·Periodontology 2000·W H Binnie
Sep 23, 2014·Journal of Medical Case Reports·Roberta MariniGian Luca Sfasciotti
Sep 6, 2005·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·F IdeK Kusama
Sep 23, 2000·British Journal of Plastic Surgery·B M RichardM W Ferguson
Feb 24, 2007·The Journal of Clinical Pediatric Dentistry·J D R PaulaL M C P Pinto
Sep 9, 2004·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Karina Mirela Ribeiro Pinto AlvesBeatriz Costa
Mar 1, 1983·Journal of Clinical Periodontology·B S Moskow, A Bloom
Oct 3, 2018·Korean journal of pediatrics·Brenda Perez-AguirreObed Garcia-Cortes
Jan 15, 2002·Pesquisa odontológica brasileira = Brazilian oral research·M H BaldaniW A Scheidt
Jan 1, 2011·International Journal of Clinical Pediatric Dentistry·Aman Moda

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