Numerical simulations of flow in cerebral aneurysms: comparison of CFD results and in vivo MRI measurements

Journal of Biomechanical Engineering
Vitaliy L RayzD Saloner


Computational fluid dynamics (CFD) methods can be used to compute the velocity field in patient-specific vascular geometries for pulsatile physiological flow. Those simulations require geometric and hemodynamic boundary values. The purpose of this study is to demonstrate that CFD models constructed from patient-specific magnetic resonance (MR) angiography and velocimetry data predict flow fields that are in good agreement with in vivo measurements and therefore can provide valuable information for clinicians. The effect of the inlet flow rate conditions on calculated velocity fields was investigated. We assessed the internal consistency of our approach by comparing CFD predictions of the in-plane velocity field to the corresponding in vivo MR velocimetry measurements. Patient-specific surface models of four basilar artery aneurysms were constructed from contrast-enhanced MR angiography data. CFD simulations were carried out in those models using patient-specific flow conditions extracted from MR velocity measurements of flow in the inlet vessels. The simulation results computed for slices through the vasculature of interest were compared with in-plane velocity measurements acquired with phase-contrast MR imaging in vivo. The se...Continue Reading


Feb 1, 1983·Journal of Biomechanical Engineering·T J KriewallB A Work
Mar 5, 1999·Critical Reviews in Biomedical Engineering·Quan LongM Bourne
Sep 29, 1999·Medical Physics·R FahrigDavid W Holdsworth
Nov 27, 1999·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·K C WangC A Taylor
Mar 30, 2000·Journal of Magnetic Resonance Imaging : JMRI·Q LongA V Stanton
Apr 4, 2001·Annals of Biomedical Engineering·J G MyersC R Ethier
Nov 13, 2001·Journal of Neurosurgery·C L TurnerP J Kirkpatrick
Nov 24, 2001·Medical Engineering & Physics·Y LiuK B Chandran
Dec 18, 2001·Journal of Magnetic Resonance Imaging : JMRI·U KöhlerPeter Hoskins
Mar 2, 2002·Journal of Biomechanical Engineering·J S StroudD Saloner
Jun 28, 2002·Annals of Biomedical Engineering·David A Steinman
Jun 28, 2002·Annals of Biomedical Engineering·J D Humphrey, S Na
Nov 27, 2002·Academic Radiology·Juan Raul CebralPeter L Choyke
Mar 26, 2003·Journal of Magnetic Resonance Imaging : JMRI·M MarklN J Pelc
Apr 22, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M MarklN J Pelc
Apr 13, 2005·IEEE Transactions on Medical Imaging·Juan Raul CebralAlejandro F Frangi
Jul 4, 2006·Journal of Biomechanical Engineering·Alvaro A ValenciaCristina H Amon
Dec 13, 2006·Journal of Biomechanical Engineering·Yiemeng HoiHui Meng
Apr 17, 2008·Journal of Biomechanical Engineering·Vitaliy L RayzD Saloner


May 26, 2010·Annals of Biomedical Engineering·Vitaliy L RayzD Saloner
Oct 22, 2011·Annals of Biomedical Engineering·Amirhossein ArzaniShawn C Shadden
Nov 29, 2012·Annals of Biomedical Engineering·Monica SigovanD Saloner
Dec 4, 2009·Briefings in Bioinformatics·Maxwell Lewis Neal, Roy Kerckhoffs
Dec 31, 2011·Journal of Biomechanical Engineering·Ian Marshall
Apr 30, 2009·Annual Review of Biomedical Engineering·C A Taylor, C A Figueroa
Nov 21, 2015·Journal of Neuroradiology. Journal De Neuroradiologie·Jérôme BergeVincent Dousset
Jan 24, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L BousselD Saloner
Nov 30, 2010·International Journal for Numerical Methods in Biomedical Engineering·Daniel M SforzaJuan Raul Cebral
Feb 15, 2013·IEEE Transactions on Medical Imaging·Alejandro F FrangiDana Brooks
Nov 1, 2011·Journal of Biomechanics·Alexander AssmannArtur Lichtenberg
Feb 3, 2016·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Lijian XuRyuhei Yamaguchi
Mar 25, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Brian P WalcottM T Lawton
Sep 5, 2014·Annals of Biomedical Engineering·Bongjae Chung, Juan Raul Cebral
Mar 24, 2018·Journal of Biomechanical Engineering·Andrea AcunaCraig J Goergen
Feb 13, 2019·NMR in Biomedicine·Thomas PuiseuxRamiro Moreno
Oct 29, 2014·Annals of Biomedical Engineering·Vitaliy L RayzM T Lawton
Mar 28, 2020·Annual Review of Biomedical Engineering·Vitaliy L Rayz, Aaron A Cohen-Gadol
May 9, 2014·The International Journal of Artificial Organs·Leonid GoubergritsUlrich Kertzscher
Jul 7, 2020·International Journal for Numerical Methods in Biomedical Engineering·Isaac Perez-RayaRoshan M D'Souza

Related Concepts

Blood Flow Velocity
Mycotic Aneurysm, Intracranial
Cerebrovascular Circulation
In Silico
Image Interpretation, Computer-Assisted
Magnetization Transfer Contrast Imaging
Blood Vessel
Magnetic Resonance Imaging

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