Numerical study of the uniformity of balloon-expandable stent deployment

Journal of Biomechanical Engineering
P MortierP Verdonck

Abstract

Stents are small tubelike structures, implanted in coronary and peripheral arteries to reopen narrowed vessel sections. This endovascular intervention remains suboptimal, as the success rate is limited by restenosis. This renarrowing of a stented vessel is related to the arterial injury caused by stent-artery and balloon-artery interactions, and a local subsequent inflammatory process. Therefore, efforts to optimize the stent deployment remain very meaningful. Several authors have studied with finite element modeling the mechanical behavior of balloon-expandable stents, but none of the proposed models incorporates the folding pattern of the balloon. We developed a numerical model in which the CYPHER stent is combined with a realistic trifolded balloon. In this paper, the impact of several parameters such as balloon length, folding pattern, and relative position of the stent with respect to the balloon catheter on the free stent expansion has been investigated. Quantitative validation of the modeling strategy shows excellent agreement with data provided by the manufacturer and, therefore, the model serves as a solid basis for further investigations. The parametric analyses showed that both the balloon length and the folding patt...Continue Reading

References

Jul 15, 1995·The American Journal of Cardiology·Y IkariT Yamaguchi
Jan 13, 1999·Circulation·A FarbR Virmani
Aug 15, 2000·Journal of Biomechanics·C Dumoulin, B Cochelin
Jun 12, 2003·Annals of Biomedical Engineering·B P MurphyD F Quinn
Dec 18, 2004·Medical Engineering & Physics·Francesco MigliavaccaGabriele Dubini
Jun 17, 2005·Journal of Biomechanics·C LallyP J Prendergast
Jun 28, 2005·The American Journal of Cardiology·Jose de Ribamar CostaMartin B Leon
Jan 13, 2006·Circulation·Thomas ThomUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Feb 3, 2006·The New England Journal of Medicine·Patrick W SerruysAndrew T L Ong
Jul 4, 2006·Journal of the American College of Cardiology·Michael JonerRenu Virmani
Jul 25, 2006·The American Journal of Cardiology·Mark J Eisenberg, Kristin J Konnyu

❮ Previous
Next ❯

Citations

Jul 1, 2010·Computer Methods in Biomechanics and Biomedical Engineering·David Martin, Fergal J Boyle
Feb 1, 2013·Journal of Biomechanical Engineering·Shijia ZhaoStacey R Froemming
Oct 22, 2008·Medical & Biological Engineering & Computing·Peter MortierBenedict Verhegghe
Sep 12, 2014·Annals of Biomedical Engineering·C ConwayP E McHugh
May 7, 2010·Annals of Biomedical Engineering·W WuF Migliavacca
Jul 19, 2012·Annals of Biomedical Engineering·Nicolas DemangetJean-Pierre Favre
Oct 24, 2012·Annals of Biomedical Engineering·Stefano Morlacchi, Francesco Migliavacca
Jan 2, 2009·Medical Engineering & Physics·Matthieu De BeuleBenedict Verhegghe
Dec 10, 2009·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Miguel A M PeiranoRobert Guidoin
Jan 15, 2017·Biomedical Engineering Online·Hongxia LiBao Zhu
Jan 2, 2009·Medical Engineering & Physics·Peter MortierPascal Verdonck
Feb 6, 2017·Biomedical Engineering Online·Hongxia LiBao Zhu
Jun 30, 2018·International Journal for Numerical Methods in Biomedical Engineering·Nelson S RibeiroHélder C Rodrigues
Sep 16, 2010·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·H B HenningerJ A Weiss
Oct 7, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Avinash Kumar, Naresh Bhatnagar
Aug 26, 2021·Cardiovascular Engineering and Technology·Ganesh B RahinjLaxminarayanan Ramanan
Sep 15, 2021·The Canadian Journal of Cardiology·Raymond N HaddadSophie Malekzadeh-Milani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.