Numerical study of wall shear stress-based descriptors in the human left coronary artery

Computer Methods in Biomechanics and Biomedical Engineering
S I S Pinto, J B L M Campos

Abstract

The present work is about the application of wall shear stress descriptors - time averaged wall shear stress (TAWSS), oscillating shear index (OSI) and relative residence time (RRT) - to the study of blood flow in the left coronary artery (LCA). These descriptors aid the prediction of disturbed flow conditions in the vessels and play a significant role in the detection of potential zones of atherosclerosis development. Hemodynamic descriptors data were obtained, numerically, through ANSYS® software, for the LCA of a patient-specific geometry and for a 3D idealized model. Comparing both cases, the results are coherent, in terms of location and magnitude. Low TAWSS, high OSI and high RRT values are observed in the bifurcation - potential zone of atherosclerosis appearance. The dissimilarities observed in the TAWSS values, considering blood as a Newtonian or non-Newtonian fluid, releases the importance of the correct blood rheologic caracterization. Moreover, for a higher Reynolds number, the TAWSS values decrease in the bifurcation and along the LAD branch, increasing the probability of plaques deposition. Furthermore, for a stenotic LCA model, very low TAWSS and high RRT values in front and behind the stenosis are observed, indi...Continue Reading

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Citations

May 26, 2017·Computer Methods in Biomechanics and Biomedical Engineering·T Barber
Jan 15, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Mahesh Nagargoje, Raghvendra Gupta
Jun 11, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Jianfei SongFarid Bakir
Feb 7, 2019·Cardiovascular Engineering and Technology·N PinhoS I S Pinto
Jan 22, 2019·Computer Methods in Biomechanics and Biomedical Engineering·B Prashantha, S Anish
Nov 24, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Violeta CarvalhoSenhorinha F C F Teixeira
Mar 16, 2021·Frontiers in Neurology·David S LiebeskindDavid J Schneider
Apr 1, 2021·Computer Methods and Programs in Biomedicine·Sreelakshmi Sandeep, S R Shine
Aug 24, 2021·Biomedical Physics & Engineering Express·Tahura HossainM Tarik Arafat
Dec 31, 2021·International Journal for Numerical Methods in Biomedical Engineering·Chen PengYun Shi

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Methods Mentioned

BETA
rheology

Software Mentioned

TAWSS
Fluent Meshing ANSYS®
Fluent ANSYS®
SKEWNESS
MIMIC
MIMICS®
SolidWorks®

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