PMID: 9188372Sep 1, 1996Paper

Nurse management of posttransplant hypertension in liver transplant patients

Journal of Transplant Coordination : Official Publication of the North American Transplant Coordinators Organization (NATCO)
L SchwartzS C Textor

Abstract

Hypertension develops soon after organ transplantation using cyclosporine- or FK506-based immunosuppression. Sustained rises in blood pressure require intervention to reduce the risk of intracranial bleeding and other cardiovascular complications. Antihypertensive treatment is complicated by reduced renal function and potential interference with absorption and/or metabolism of cyclosporine or FK506. To manage early and long-term hypertension related to immunosuppression with cyclosporine or FK506 and prednisone following orthotopic liver transplantation, a comprehensive nurse-managed hypertension clinic was developed. Blood pressure, heart rate, and antihypertensive and immunosuppressive regimens were evaluated according to a standard protocol at 1, 4, 12, 24, and 36 months after orthotopic liver transplantation. Data indicate that posttransplantation hypertension develops within the first months after orthotopic liver transplantation and persists indefinitely. If comprehensively managed by the hypertension nurse-clinician, the percentage of controlled hypertension patients can increase over time.

References

May 1, 1991·American Journal of Hypertension·R G Luke
Sep 1, 1990·American Journal of Hypertension·D A Laskow, J J Curtis
Jan 1, 1990·Mayo Clinic Proceedings·L L SchwartzD T Muenter
Oct 1, 1994·Mayo Clinic Proceedings·C A Nash
Dec 1, 1994·Mayo Clinic Proceedings·S C TextorR A Krom

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Citations

Nov 25, 2014·Journal of Cellular Biochemistry·Sara DamianoAntonio Giordano
Jul 13, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Olaf GuckelbergerPeter Neuhaus
Jul 3, 1998·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·V J CanzanelloR A Krom
Jul 23, 2003·Journal of the American Society of Nephrology : JASN·Stephen C TextorMark Stegall
Mar 15, 2000·Transplantation Proceedings·S Semhoun-DuclouxJ Miguet

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