Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses

High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension
Arrigo F G Cicero, Alessandro Colletti

Abstract

Beyond the well-known effects on blood pressure (BP) of the dietary approaches to stop hypertension (DASH) and the Mediterranean diets, a large number of studies has investigated the possible BP lowering effect of different dietary supplements and nutraceuticals, the most part of them being antioxidant agents with a high tolerability and safety profile. In particular relatively large body of evidence support the use of potassium, L-arginine, vitamin C, cocoa flavonoids, beetroot juice, coenzyme Q10, controlled-release melatonin, and aged garlic extract. However there is a need for data about the long-term safety of a large part of the above discussed products. Moreover further clinical research is advisable to identify between the available active nutraceuticals those with the best cost-effectiveness and risk-benefit ratio for a large use in general population with low-added cardiovascular risk related to uncomplicated hypertension.

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Citations

Jan 19, 2016·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Arrigo F G Cicero, Alessandro Colletti
Feb 19, 2016·Molecular Nutrition & Food Research·Asimina Kerimi, Gary Williamson
Nov 1, 2016·Current Cardiology Reports·Jeffrey M Turner, Erica S Spatz
Aug 31, 2016·British Journal of Pharmacology·Arrigo F G CiceroAlessandro Colletti
May 26, 2017·Food & Function·Arrigo F G CiceroAlessandro Colletti
Jan 21, 2018·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Arrigo F G CiceroAlessandro Colletti
Jan 24, 2019·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Arrigo F G CiceroClaudio Ferri
Feb 2, 2018·Critical Reviews in Food Science and Nutrition·Domancar Orona-TamayoOctavio Paredes-López
Jan 24, 2018·Critical Reviews in Food Science and Nutrition·Federica FogacciArrigo F G Cicero
Nov 25, 2018·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Arrigo F G CiceroClaudio Borghi
Jan 21, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Vasso ApostolopoulosIstvan Toth
Jan 21, 2020·Food Research International·Samad Ghaffari, Neda Roshanravan
Apr 13, 2021·Brain, Behavior, & Immunity Health·Thomas RitzAnnie T Ginty

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