Nutrient supplementation during the first 1000 days and growth of infants born to pregnant adolescents

Annals of the New York Academy of Sciences
Kathryn G DeweyCharles D Arnold

Abstract

Few studies have evaluated the impact of nutritional supplementation among pregnant adolescents. We examined the effects of the Rang Din Nutrition Study (RDNS) interventions on children born to mothers <20 years of age. The RDNS was a cluster-randomized effectiveness trial with four arms: (1) women and children both received small-quantity lipid-based nutrient supplements (LNS-LNS), (2) women received iron and folic acid (IFA) and children received LNS (IFA-LNS), (3) women received IFA and children received micronutrient powder (MNP) (IFA-MNP), and (4) women received IFA and children received no supplements (IFA-Control). We enrolled 4011 women at <20 weeks gestation; 1552 were adolescents. Among adolescents, prenatal LNS reduced newborn stunting by 25% and small head size by 28% and had a marginally significant effect on newborn wasting, compared with IFA. Low birth weight and preterm birth were reduced only among adolescents with lower food security. Effects on subsequent growth status were observed only among female children in the LNS-LNS group: less stunting at 18 months (versus IFA-MNP) and lower prevalence of small head circumference and wasting at 24 months (versus IFA-Control). Initiatives targeting pregnant adolescent...Continue Reading

References

Oct 1, 1990·American Journal of Obstetrics and Gynecology·J Villar, J T Repke
Nov 1, 1989·The American Journal of Clinical Nutrition·F F CherryX B Wang
Jun 1, 1981·Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine·D M PaigeL Davis
Aug 1, 1997·Obstetrics and Gynecology·P López-JaramilloJ Rivera
May 6, 2003·The Journal of Nutrition·Carlos Castillo-Durán, Gerardo Weisstaub
Jul 7, 2012·Paediatric and Perinatal Epidemiology·Cassandra M GibbsCarol J Hogue
May 31, 2013·The American Journal of Clinical Nutrition·Maria Eduarda L DiogenesCarmen M Donangelo
Jun 12, 2013·Lancet·Robert E BlackUNKNOWN Maternal and Child Nutrition Study Group
Sep 6, 2013·Child Maltreatment·Scott D EastonM V Moorthy
Mar 20, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·T GanchimegUNKNOWN WHO Multicountry Survey on Maternal Newborn Health Research Network
Dec 3, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·W Johnson, S E Moore
Jan 25, 2017·American Journal of Human Biology : the Official Journal of the Human Biology Council·Reynaldo Martorell
Apr 25, 2017·Annals of the New York Academy of Sciences·Zohra S LassiZulfiqar A Bhutta
Apr 25, 2017·Annals of the New York Academy of Sciences·Jai K DasZulfiqar A Bhutta
Oct 19, 2017·Annals of the New York Academy of Sciences·Alyssa FriebertMark J Manary
Jan 24, 2018·Pediatrics·Sarah Jane SchwarzenbergUNKNOWN COMMITTEE ON NUTRITION

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Methods Mentioned

BETA
SGA

Clinical Trials Mentioned

NCT01715038

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