Nutrigenomics, proteomics, metabolomics, and the practice of dietetics

Journal of the American Dietetic Association
Elaine TrujilloJohn A Milner

Abstract

The human genome is estimated to encode over 30,000 genes, and to be responsible for generating more than 100,000 functionally distinct proteins. Understanding the interrelationships among genes, gene products, and dietary habits is fundamental to identifying those who will benefit most from or be placed at risk by intervention strategies. Unraveling the multitude of nutrigenomic, proteomic, and metabolomic patterns that arise from the ingestion of foods or their bioactive food components will not be simple but is likely to provide insights into a tailored approach to diet and health. The use of new and innovative technologies, such as microarrays, RNA interference, and nanotechnologies, will provide needed insights into molecular targets for specific bioactive food components and how they harmonize to influence individual phenotypes. Undeniably, to understand the interaction of food components and gene products, there is a need for additional research in the "omics" of nutrition. It is incumbent upon dietetics professionals to recognize that an individual's response to dietary intervention will depend on his or her genetic background and that this information may be used to promote human health and disease prevention. The obje...Continue Reading

References

Mar 15, 2001·Diabetes·J LuanN J Wareham
Sep 13, 2001·Cancer Causes & Control : CCC·S A InglesR W Haile
Oct 31, 2001·The American Journal of Clinical Nutrition·P B RapuriK L Ryschon
Mar 7, 2002·The Journal of Nutrition·Coral A LamartiniereAda Elgavish
Aug 7, 2002·The Journal of Nutrition·Craig A CooneyGeorge L Wolff
Oct 17, 2002·JAMA : the Journal of the American Medical Association·Paul K WheltonUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Apr 3, 2003·Nature Reviews. Genetics·Michael Müller, Sander Kersten
Apr 25, 2003·The New England Journal of Medicine·Eugenia E CalleMichael J Thun
May 2, 2003·Annals of the New York Academy of Sciences·Sharon A Ross
May 6, 2003·The Journal of Nutrition·Bruce N Ames
Oct 22, 2003·Primary Care·George A Bray
Nov 5, 2003·Pharmacogenomics·Ruhong JiangChuanbo Xu
Jan 9, 2004·Endocrinology and Metabolism Clinics of North America·George A Bray
Jan 17, 2004·Physiological Genomics·Jim Kaput, Raymond L Rodriguez
May 1, 2004·Science·Jennifer Couzin
May 22, 2004·Nature Reviews. Genetics·UNKNOWN International HapMap Consortium
Jul 13, 2004·The Journal of Urology·Yasushi IchimuraTetsuro Kato
Jul 15, 2004·International Journal of Cancer. Journal International Du Cancer·Martha L SlatteryWade Samowitz
Sep 15, 2004·Genome Research·Robert J LivingstonDeborah A Nickerson
Oct 14, 2004·Nutrition Reviews·Javier CampiónJ Alfredo Martínez
Oct 16, 2004·Annual Review of Genomics and Human Genetics·Jose M Ordovas, Dolores Corella
Nov 24, 2004·Biological Trace Element Research·Ya Jun HuAlan M Diamond
Mar 10, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Baukje de RoosBas Teusink
Mar 15, 2005·The Journal of Biological Chemistry·Shivendra V SinghAnna Herman-Antosiewicz
Apr 2, 2005·Nature Reviews. Genetics·David J Hunter
May 25, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Lorraine C LoweKay W Colston

❮ Previous
Next ❯

Citations

Jul 3, 2013·Molecular Neurobiology·Ashraf VirmaniSyed Ali
Dec 1, 2008·Journal of Cardiovascular Translational Research·Jackie L BoucherTimothy D Henry
Mar 3, 2009·Journal of the American Dietetic Association·Ruth DeBusk
Jun 25, 2008·The British Journal of Nutrition·Siegfried KnasmüllerKarl-Heinz Wagner
Jan 1, 2014·Journal of Agricultural and Food Chemistry·Luciana S GomesEliane Fialho
Feb 21, 2013·Journal of Proteome Research·Guoxiang XieWei Jia
Oct 25, 2008·Critical Reviews in Food Science and Nutrition·Gregory Tucker, Kevin Robards
Oct 13, 2006·Antioxidants & Redox Signaling·D Allan Butterfield
Dec 2, 2008·Omics : a Journal of Integrative Biology·Nola M Ries, David Castle
Aug 3, 2007·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Jeffrey W Elias, Molly V Wagster
Aug 29, 2007·Acta Pharmacologica Sinica·Cindy D Davis, John A Milner
Jul 7, 2009·Annual Review of Nutrition·Gianni Panagiotou, Jens Nielsen
Jun 1, 2011·Journal of Nutrigenetics and Nutrigenomics·Michael FenechRichard Head
Dec 25, 2009·Circulation. Cardiovascular Genetics·Dolores Corella, Jose M Ordovas
Jan 10, 2013·PLoS Computational Biology·David S Wishart
Oct 14, 2008·Genes & Nutrition·Christine M WilliamsBen van Ommen
Nov 13, 2009·Nutrition Reviews·Rubhana Raqib, Alejandro Cravioto
Jun 16, 2009·Japanese Journal of Clinical Oncology·Po Kuei WuTain Hsiung Chen
Nov 17, 2009·Japanese Journal of Clinical Oncology·Leo KagerStefan Bielack
Feb 7, 2016·Analytica Chimica Acta·Luis Cuadros-RodríguezAntonio González-Casado
Aug 5, 2016·Metabolomics : Official Journal of the Metabolomic Society·Andreea GeamanuLobelia Samavati
Nov 13, 2010·Free Radical Biology & Medicine·Archana UnnikrishnanAhmad R Heydari
May 11, 2010·Explore : the Journal of Science and Healing·Gary DengKathi J Kemper
Mar 18, 2010·The Journal of Nutritional Biochemistry·Valerio CostaAlfredo Ciccodicola
Jan 20, 2016·BioMed Research International·Emanuele FerriMassimo Labra
May 27, 2008·Journal of the American Dietetic Association·Gail P A Kauwell
Aug 24, 2007·Journal of the American Dietetic Association·Riva Touger-DeckerUNKNOWN American Dietetic Association
Feb 7, 2008·Physiologia Plantarum·Robert D HallMelissa A Fitzgerald
Feb 20, 2016·The Journal of Nutrition, Health & Aging·A Fardet, E Rock
Aug 26, 2014·Biochimica Et Biophysica Acta·Daniel G CoxMark T Hamann
May 29, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Juliana Mara SerpeloniLusânia Maria Greggi Antunes
Oct 29, 2008·Journal of the American Dietetic Association·Stephen Barnes
May 4, 2007·Nutrition and Cancer·John A Milner
Jul 28, 2006·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Sheila M Campbell
Mar 9, 2017·Critical Reviews in Food Science and Nutrition·Arun KumarNeemisha Pathania
Feb 4, 2016·Revista da Associação Médica Brasileira·Gabriela HalpernAlexander Kopelman
Jan 18, 2017·Nutrition and Cancer·Wissam Zam, Aziz Khadour
Feb 16, 2010·Current Opinion in Lipidology·Patrick J StoverCarol M Hamilton
Mar 21, 2017·Current Pharmaceutical Design·Rosa Perez-Gregorio, Jesus Simal-Gandara

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Cancer Epigenetics and Senescence (Keystone)

Epigenetic changes are present and dysregulated in many cancers, including DNA methylation, non-coding RNA segments and post-translational protein modifications. The epigenetic changes may be involved in regulating senescence in cancer cells. This feed captures the latest research on cancer epigenetics and senescence.

Cancer -Omics

A variety of different high-throughput technologies can be used to identify the complete catalog of changes that characterize the molecular profile of cohorts of tumor samples. Discover the latest insights gained from cancer 'omics' in this feed.

Breast Cancer: Risk Factors

Breast cancer is a multifactorial disease that is influenced by both environmental and genetic factors. Discover the latest research on the environmental and genetic risk factors for breast cancer here.

Cancer Epigenetics & Metabolism (Keystone)

Epigenetic changes are present and dysregulated in many cancers, including DNA methylation, non-coding RNA segments and post-translational protein modifications. The epigenetic changes may or may not provide advantages for the cancer cells. This feed focuses on the relationship between cell metabolism, epigenetics and tumor differentiation.

Cancer Genomics (Keystone)

Cancer genomics approaches employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research using such technologies in this feed.

Related Papers

Journal of the American Dietetic Association
Lydia Afman, Michael Müller
Journal of the American Dietetic Association
Ruth M DebuskKenneth S Kornman
Journal of the American Dietetic Association
Gail P A Kauwell
Journal of the American Dietetic Association
Lynnette R Ferguson
© 2021 Meta ULC. All rights reserved