Nutrition and miscarriages: a literature review

Gynécologie, obstétrique & fertilité
A BenammarR Levy

Abstract

Miscarriage concerns approximately 15% of pregnancies and recurrent fetal loss (RFL) constitute a particular situation concerning approximately 1% of women. The etiologic inquiry is often disappointing. Nutritional factors represent a promising aspect, insufficiently investigated even if numerous studies underline their impact on fertility, gametogenesis, embryonic development and pregnancies outcome. Obesity is considered as an independent risk factor for miscarriage, involved in oocyte and embryo quality, but also in endometrial receptivity. The male part involved in miscarriage was for a long time underestimated, neglecting the role of sperm in embryo development. If conventional sperm analysis remains essential, new investigations have to be considered such as sperm DNA or oxidant stress evaluation. It is particularly important to take into account nutritional factors as favoring miscarriage because they represent a flexible factor on which intervention is possible to improve pregnancy outcome, with toxics eviction and recommendations for diversified and well-balanced food. At last, effects of nutritional complements for miscarriage prevention remain controversial.

References

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Citations

Aug 15, 2013·Obstetrical & Gynecological Survey·Jaume Alijotas-Reig, Carmen Garrido-Gimenez
Feb 15, 2015·Postgraduate Medical Journal·Carmen Garrido-Gimenez, Jaume Alijotas-Reig
Nov 3, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Asher BashiriYael Baumfeld
Jul 14, 2020·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Anne-Solenn JacamonJérémie Thereaux

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