PMID: 2122033Sep 1, 1990Paper

Nutrition and translocation

JPEN. Journal of Parenteral and Enteral Nutrition
J W Alexander

Abstract

It is now clear that atrophy of the intestinal mucosa can occur rapidly after injury and that the degree of atrophy is quantitatively related to the severity of injury. Such atrophy can be associated with translocation of bacteria and endotoxin, which can trigger the hypermetabolic response and induce a septic state, which may ultimately lead to multiple system organ failure. Early enteral feeding following trauma can prevent atrophy of the intestinal mucosa and is associated with a decrease in the hypermetabolic response and the incidence of septic complications and diarrhea. Enteral feeding of complete diets can also improve outcome with other forms of intestinal injury such as gamma irradiation or cytotoxic drugs. In contrast, total parenteral nutrition and elemental enteral diets are associated with atrophy of the intestinal mucosa and increased translocation. The addition of glutamine and/or fiber to elemental diets may decrease translocation in some but not all circumstances. It is now clear that enteral nutrition can influence the incidence and severity of translocation, which in turn can potentially reverse or prevent the adverse effects of injury and inflammation in traumatic injury and serious illness.

References

Jan 1, 1990·The Journal of Surgical Research·W W SoubaE M Copeland
Mar 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·S A KripkeJ L Rombeau
Jul 1, 1989·The Journal of Trauma·F A MooreV M Peterson
Jul 1, 1989·The Journal of Burn Care & Rehabilitation·S InoueE B Silberstein
Nov 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·S InoueP Gura
Sep 1, 1989·Gut·D G MaxtonR P Thompson
Sep 1, 1988·Reviews of Infectious Diseases·C L WellsR L Simmons
Mar 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·O TrockiJ W Alexander
Jul 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·A D FoxJ L Rombeau
May 1, 1988·The Journal of Surgical Research·S InoueR R Cardell

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Citations

Feb 22, 1992·Lancet·P D Macnaughton, T W Evans
Aug 1, 1994·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·M BragaV Di Carlo
Sep 1, 1993·Anaesthesia·J P Fee
Feb 21, 1998·Journal of Veterinary Internal Medicine·J DahlingerD C Hirsh
Aug 25, 2009·Applied and Environmental Microbiology·Kei SonoyamaTatsuya Morita
Mar 20, 1998·Gut·C J O'BoyleP C Sedman
Aug 1, 1996·AACN Clinical Issues·J Krenitsky
Jun 12, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·G C BriassoulisT D Hatzis MD
Jun 1, 1995·Diseases of the Colon and Rectum·P M SagarD Johnstone
Jan 15, 1998·Critical Care Medicine·W WangI H Chaudry
Feb 1, 1995·Scandinavian Journal of Gastroenterology·M WirénJ Larsson
Sep 1, 1994·Gastroenterology·P C SedmanD Johnstone
May 11, 1992·The Journal of Surgical Research·W J FlynnR N Garrison
Feb 1, 1991·American Journal of Surgery·F B Cerra
Aug 23, 2000·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J CohenP Singer
Feb 19, 2014·Orvosi hetilap·Olivér RoseroAttila Szijártó
Apr 25, 2000·The Journal of Hospital Infection·A O Qamruddin, P R Chadwick
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·A A MascleeC B Lamers
Nov 1, 1995·JPEN. Journal of Parenteral and Enteral Nutrition·A L BuchmanS R Vijayaroghavan
Apr 1, 1997·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·C FordJ B Pietsch
Aug 1, 1995·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·K Ringwald-SmithL Stricklin
Oct 6, 2001·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·J Deswarte-WallaceJ Z Finklestein
Apr 6, 2001·AACN Clinical Issues·S J StoneJ T Jesurum
Jan 23, 1999·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·T TuğI Kuzu
Sep 15, 2012·Journal of the Korean Surgical Society·Jun-Gyo GwonSuk-Kyung Hong
Jul 11, 2006·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jorge S Sasbón, Gustavo Cardigni
May 4, 2007·Nature Clinical Practice. Gastroenterology & Hepatology·Khursheed N Jeejeebhoy
Sep 1, 1996·Archives of Disease in Childhood·A PapadopoulouI W Booth
Oct 26, 1991·BMJ : British Medical Journal·N D Maynard, D J Bihari
Dec 1, 1994·Gut·A P Jenkins, R P Thompson
Jan 11, 2007·Journal of Burn Care & Research : Official Publication of the American Burn Association·Gary F Purdue
Jan 23, 2009·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Pengfei WangJieshou Li
Apr 17, 1999·Journal of Pediatric Hematology/oncology·J B PietschJ A Whitlock
Mar 1, 1994·The Proceedings of the Nutrition Society·M Elia
Apr 1, 1994·Scandinavian Journal of Gastroenterology·X Wang, R Andersson

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