Hematopoietic stem cell transplant (HSCT) patients can present a number of nutrition challenges despite recent advancements in medical care. Several areas of controversy exist, including whether probiotics can be safely used; the use of probiotics continues to expand but efficacy and safety is a concern in immunocompromised patients, including HSCT recipients. Second, parenteral nutrition continues to be the primary avenue for nutrition support despite growing evidence that enteral feedings can be successfully administered. Last, tight glycemic control has been associated with positive clinical outcomes in hospitalized patients. However, whether tight glycemic control can be achieved and is of benefit in this patient population continues to be debated. This article will discuss the current challenges facing clinicians regarding these 3 issues-probiotics, enteral nutrition support, and glycemic control-and future directions in HSCT.
Hyperalimentation in autologous bone marrow transplantation for solid tumors. Comparison of total parenteral versus partial parenteral plus enteral nutrition
Detection by polymerase chain reaction of BCR/ABL transcripts in myeloproliferative diseases at time of diagnosis and for monitoring chronic myelogenous leukaemia patients after bone marrow transplantation
Detection of plasma (1 --> 3)-beta-D-glucan in patients with Fusarium, Trichosporon, Saccharomyces and Acremonium fungaemias
Simple strategy for direct identification of medically important yeast species from positive blood culture vials
Parenteral nutrition following intensive cytotoxic therapy: an exploratory study on the need for parenteral nutrition after various treatment approaches for haematological malignancies
Persistent Lactobacillus casei subspecies rhamnosus bacteremia in a 14 year old girl with acute myeloid leukemia. A case report
Efficacy and safety of radiologically placed gastrostomy tubes in paediatric haematology/oncology patients
Saccharomyces fungemia complicating Saccharomyces boulardii treatment in a non-immunocompromised host
Fungemia with Saccharomyces cerevisiae in two newborns, only one of whom had been treated with ultra-levura
Hypocaloric total parenteral nutrition: effectiveness in prevention of hyperglycemia and infectious complications--a randomized clinical trial
Mucositis associated with stem cell transplantation: current status and innovative approaches to management
Home care during the pancytopenic phase after allogeneic hematopoietic stem cell transplantation is advantageous compared with hospital care.
Saccharomyces cerevisiae fungemia after Saccharomyces boulardii treatment in immunocompromised patients
Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control
Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting
Six cases of Lactobacillus bacteraemia: identification of organisms and antibiotic susceptibility and therapy
Impact of clinical pharmacist-based parenteral nutrition service for bone marrow transplantation patients: a randomized clinical trial
Clinical impact of systematic nutritional care in adults submitted to allogeneic hematopoietic stem cell transplantation
Predictors of gastrostomy placement in children with inherited metabolic diseases treated by umbilical cord blood transplantation
Obesity is associated with higher overall survival in patients undergoing an outpatient reduced-intensity conditioning hematopoietic stem cell transplant
Comment on "Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study"
Nutritional issues and body weight in long-term survivors of allogeneic blood and marrow transplant (BMT) in NSW Australia
Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells.
The Systemic Metabolic Profile Early after Allogeneic Stem Cell Transplantation: Effects of Adequate Energy Support Administered through Enteral Feeding Tube.
Systematic review of gastrostomy complications and outcomes in pediatric cancer and bone marrow transplant.
Blood And Marrow Transplantation
The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.
Allogenic & Autologous Therapies
Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.