Nutritional intervention in patients with periodontal disease: clinical, immunological and microbiological variables during 12 months

The British Journal of Nutrition
Axel JenzschHolger Jentsch

Abstract

The role of nutrition in onset, progression and treatment of periodontitis has not been thoroughly evaluated. In the present prospective clinical study, we investigated the influence of a nutritional intervention on changes in clinical, microbiological and immunological periodontal variables during a period of 12 months in patients with the metabolic syndrome and chronic periodontitis. Twenty female subjects with the metabolic syndrome and mild to moderate chronic periodontitis participated in a guided nutritional intervention programme. Examinations were assessed before, and at 2 weeks, 3, 6 and 12 months after intervention. Clinical measurements included probing depth, Löe and Silness gingival index and Quigley-Hein plaque index. In gingival crevicular fluid, periodontopathogens, levels of IL-1beta and IL-6 as well as the activity of granulocyte elastase were determined. In stimulated saliva, antioxidative and oxidative variables were measured. After 12 months the following significant changes could be observed: reduction of clinical probing depth (2.40 v. 2.20 mm; P < 0.001), reduction of gingival inflammation (gingival index 1.13 v. 0.9; P < 0.001), reduced concentrations of IL-1beta (4.63 v. 1.10 pg/ml per site; P < 0.001)...Continue Reading

References

Sep 1, 1977·Scandinavian Journal of Haematology·J PalmbladS Rössner
Aug 23, 1976·Biochemical and Biophysical Research Communications·R A Lawrence, R F Burk
Sep 11, 1991·Archives of Biochemistry and Biophysics·I de MendezC R Lambré
Dec 1, 1991·Journal of Periodontology·K T Miyasaki
Jan 1, 1990·Methods in Enzymology·H Esterbauer, K H Cheeseman
Mar 15, 1989·The Biochemical Journal·B Davies, S W Edwards
Jan 1, 1970·Journal of Periodontology·S TureskyI Glickman
Jan 1, 1984·Journal of Clinical Periodontology·D R MillerA I Chasens
Feb 1, 1995·The American Journal of Clinical Nutrition·C O Enwonwu
Jun 1, 1995·Community Dentistry and Oral Epidemiology·T K SakkiM S Hartikainen
Jul 1, 1994·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·O I Aruoma
Feb 1, 1994·Journal of Periodontology·G C ArmitageT J Sharp
Jul 31, 1998·Nutrition·R F Grimble
Oct 28, 1998·Environmental Health Perspectives·Y S HoJ Cao
Aug 19, 1999·European Journal of Clinical Nutrition·A JenkinsonG G Duthie
Jul 17, 2001·Journal of Periodontal Research·T AlpagotD W Chambers
Oct 13, 2001·Journal of Dental Research·T SaitoA Ohshima
May 11, 2002·The Proceedings of the Nutrition Society·Dean V Sculley, Simon C Langley-Evans
Aug 31, 2002·Journal of Clinical Microbiology·Ashraf F FouadJustin D Radolf
Nov 28, 2002·JAMA : the Journal of the American Medical Association·Frank B Hu, Walter C Willett
Apr 18, 2003·Dental Clinics of North America·Linda D Boyd, Theresa E Madden
Apr 26, 2003·Nutrition·Christine S Ritchie, Denis F Kinane
Jun 21, 2003·Journal of Periodontology·Mohammad S Al-ZahraniElaine A Borawskit
Dec 1, 1963·Acta Odontologica Scandinavica·H LOE, J SILNESS
Mar 9, 2005·Annals of the New York Academy of Sciences·Dayong WuSimin Nikbin Meydani
Aug 18, 2005·Journal of Periodontal Research·C C TsaiC C Hung
Sep 1, 2005·Journal of Clinical Periodontology·Bruno G LoosMarja L Laine
Oct 21, 2005·Public Health Nutrition·Claus Leitzmann
Feb 14, 2006·Diabetes Technology & Therapeutics·Lucy M Browning, Susan A Jebb
Jun 10, 2006·The American Journal of Clinical Nutrition·Anwar T MerchantKaumudi J Joshipura
Jun 27, 2006·Journal of Dental Research·L KesavaluJ L Ebersole
Aug 15, 2006·Journal of the American College of Cardiology·Dario GiuglianoKatherine Esposito

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Citations

May 30, 2013·European Journal of Clinical Nutrition·I StaufenbielH Günay
Oct 27, 2011·European Journal of Medical Research·Brita WillershausenA Callaway
Jun 2, 2014·Archives of Oral Biology·Keiko Watanabe, Yale D Cho
Sep 21, 2013·Homeopathy : the Journal of the Faculty of Homeopathy·S FarrerR T Mathie
Aug 23, 2012·Periodontology 2000·Cyril O Enwonwu, Nathanael Salako
Mar 1, 2011·Journal of Clinical Periodontology·Maurizio S TonettiUNKNOWN Working Group 3 of Seventh European Workshop on Periodontology
Feb 26, 2011·Journal of Clinical Periodontology·U Van der VeldenI L C Chapple
Dec 11, 2013·Periodontology 2000·Dolphus R DawsonJeffrey L Ebersole
Dec 10, 2013·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·A Zare JavidP J Moynihan
Mar 24, 2015·Diabetes & Metabolic Syndrome·H HatipogluY Gungor
Nov 4, 2016·Journal of Clinical Periodontology·Leena JauhiainenPekka Ylöstalo
Feb 9, 2018·Journal of Clinical Periodontology·Leena M JauhiainenPekka V Ylöstalo
May 16, 2018·Journal of Clinical Periodontology·Masanori IwasakiHideo Miyazaki
Jun 13, 2014·Journal of Periodontal & Implant Science·Jaeri LeeChang-Sung Kim
Oct 27, 2018·Journal of Clinical Periodontology·Mayte Martinez-HerreraMilagros Rocha
Apr 10, 2010·Expert Review of Anti-infective Therapy·Kei E FujimuraSusan V Lynch
Apr 12, 2013·Periodontology 2000·Robert J Genco, Wenche S Borgnakke
May 10, 2020·Periodontology 2000·Søren JepsenJames Deschner
Jul 17, 2021·Clinical, Cosmetic and Investigational Dentistry·Simona SantonocitoGaetano Isola

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