Nutritional Supplementation for the Prevention and/or Treatment of Gestational Diabetes Mellitus

Current Diabetes Reports
Jasmine F PlowsJoanna L Stanley

Abstract

Gestational diabetes mellitus (GDM) is a common pregnancy complication that has short- and long-term health implications for both the mother and child. While lifestyle modifications, insulin therapy, and oral agents such as metformin are effective, they can be difficult to adhere to, and there remain concerns over long-term effects of oral agents on the infant. Further, GDM has no proven preventive strategies, which could be more effective than treatment postdiagnosis. Nutritional supplements are an appealing, potentially safer, and better tolerated alternative to pharmaceuticals to treat and/or prevent GDM. Here, we review the existing evidence for nutritional supplementation for treatment and prevention of GDM. There is limited evidence that myo-inositol, vitamins D and B6, magnesium, selenium, zinc, fatty acids, and probiotics might be beneficial for the prevention or treatment of GDM. There are very few studies for each nutrient, and the existing studies tend to have few participants. Where multiple studies of a nutrient exist, often those studies were conducted within the same country, limiting the generalizability of the findings, or alternatively there was no consensus across findings. There is limited evidence that nutr...Continue Reading

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Citations

Jan 23, 2020·The British Journal of Nutrition·Komal ManerkarChristopher McKinlay
Dec 12, 2019·Hormones : International Journal of Endocrinology and Metabolism·Lutz Schomburg
Jan 15, 2021·Biological Trace Element Research·Hasan EroğluDilek Şahin
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Nov 30, 2020·The Journal of Nutritional Biochemistry·Sergio Montserrat-de la PazVictor Sánchez-Margalet
Dec 31, 2020·International Journal of Environmental Research and Public Health·Nasloon AliLuai A Ahmed
Jan 23, 2021·International Journal of Clinical Practice·Nikolaos MachairiotisAnastasios Malakasis
Apr 20, 2021·The Cochrane Database of Systematic Reviews·Sarah J DavidsonMarloes Dekker Nitert
Aug 28, 2021·Nutrients·Maria Letizia PetroniFederico Ravaioli

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