Nux vomica 30 prepared with and without succession shows antialcoholic effect on toads and distinctive molecular association

The British Homoeopathic Journal
N C SukulS P Sinhababu

Abstract

Adult toads, Bufo melanostictus, were administered Nux vomica (Nux v) 30 prepared with and without succussion on the tongue. The drug was mixed with sterile distilled water at the rate 0.05ml/ml water and given orally 0.05ml/individual. The control consisted of blank ethanol solution. Seeds of Strychnos nuxvomica were ground and extracted with 90% ethanol in the laboratory. Nux v 30 was prepared by successive dilution and succussion in 30 steps, Nux v 30 u was prepared by successive dilution only. Four hours after treatment, toads were given 25% ethanol i.p. at 8g/kg body weight. The duration of ethanol induced sleep time was recorded for each toad. Both Nux v 30 and Nux v 30 u significantly reduced ethanol induced sleep time in toads as compared to their respective controls. Electronic, infra red and nuclear magnetic resonance spectra of Nux v 30, Nux v 30 u and their diluent medium (90% ethanol) show marked differences from each other. These dilutions and ethanol 30 and ethanol 30 u show marked differences from each other with respect to spin-lattice relaxation time (T1) and chemical shift. The difference has been attributed to the variation in intra and inter-molecular association of ethanol and water.

Citations

Nov 25, 2003·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·N C SukulA Sukul
Nov 22, 2005·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·N C SukulS P Sinhababu
May 29, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Ursula WolfStephan Baumgartner
Feb 13, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Sabine D KleinUrsula Wolf
Jan 21, 2014·Homeopathy : the Journal of the Faculty of Homeopathy·Paolo BellaviteAnita Conforti
Jan 30, 2018·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Sabine D KleinAlexander Tournier
Feb 13, 2004·Homeopathy : the Journal of the Faculty of Homeopathy·German Guajardo
Apr 11, 2012·International Journal of Molecular Sciences·Elaine C IveLalini Reddy
Jul 11, 2019·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Alexander TournierStephan Baumgartner
Oct 31, 2020·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Alexander TournierStephan Baumgartner

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