Obese type 2 diabetics and obese patients have comparable plasma phospholipid fatty acid compositions deviating from that of healthy individuals

Prostaglandins, Leukotrienes, and Essential Fatty Acids
Y RodríguezA B Christophe


There exist controversial reports regarding the differences in phospholipid fatty acids in type 2 diabetic and obese patients as compared to controls. The study was aimed at assessing the combined effect of type 2 diabetes and obesity on the fatty acid composition of plasma phospholipids. The experimental group consisted of 23 Belgian obese type 2 diabetics on Metformin. Two control groups were used: healthy lean and obese individuals in the same BMI range as the diabetics. Plasma phospholipids were isolated and their fatty acids and vinyl ether moieties were determined. Significance was set at P < 0.01. Plasma phospholipid fatty acids and plasmalogen-derived dimethyl acetals in diabetics deviated in many respects from these of lean controls but were not significantly different from those of obese non-diabetic patients. Therefore, the deviations of the fatty acid pattern of plasma phospholipids in type 2 diabetes may be attributed to obesity rather than to diabetes itself.


Feb 1, 1989·Metabolism: Clinical and Experimental·T PelikánováL Kazdová
Apr 1, 1967·Clinica Chimica Acta; International Journal of Clinical Chemistry·A Christophe, F Matthijs
Nov 1, 1994·Prostaglandins, Leukotrienes, and Essential Fatty Acids·C AgostoniM Giovannini
Dec 1, 1995·The Journal of Clinical Investigation·D A PanL H Storlien
Aug 1, 1996·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·P D'HondtR Desnyder
Dec 1, 1995·Computer Methods and Programs in Biomedicine·F SchoonjansF H Comhaire
Jul 13, 2000·The British Journal of Nutrition·B Vessby
Dec 6, 2001·Metabolism: Clinical and Experimental·T PelikánováJ Base
Apr 30, 2003·Diabetes Care·José-Manuel Fernández-RealWifredo Ricart
Sep 5, 2003·Hormone Research·Niels MøllerJakob Gjedsted
Dec 25, 2003·The Proceedings of the Nutrition Society·E E Blaak

❮ Previous
Next ❯


Apr 2, 2015·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K FeketeT Decsi
Jan 21, 2021·Journal of Cellular Physiology·Hossein Roghani-ShahrakiAbolfazl Mousavi
May 10, 2019·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Xiaomeng SunLi Yang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.