Obesity: a review of pathogenesis and management strategies.

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
Brinderjit Kaila, Maitreyi Raman

Abstract

The prevalence of obesity in the developed world is increasing. Approximately 23% of adult Canadians (5.5 million people) are obese. Obesity is associated with an increased risk of developing several comorbid diseases, ranging from cardiovascular diseases to cholelithiasis and nonalcoholic fatty liver disease. The etiology of obesity is multifactorial, involving a complex interaction among genetics, hormones and the environment. The available evidence and recommendations for nonpharmacological management of obesity, including dietary therapy, physical activity and behavioural therapy, in addition to pharmacotherapy are discussed. A brief discussion on endoscopic and surgical procedures is undertaken. Several antiobesity treatment options are available and may be indicated in appropriate situations. Selecting obesity therapy may be guided by body mass index measurements, comorbid illnesses and patient preference.

Citations

Sep 22, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Moragot Chatatikun, Wiyada Kwanhian
Dec 10, 2009·Expert Opinion on Drug Safety·Katie S McClendonGabriel Ikponmosa Uwaifo
May 6, 2017·Obesity·Alexander P GabrielliMerlin G Butler
Oct 24, 2018·The World Journal of Men's Health·Ana Dias MartinsAshok Agawal
Mar 9, 2019·Food Science & Nutrition·Irushika T FernandoLalith Jayasinghe
May 26, 2009·Regulatory Toxicology and Pharmacology : RTP·V Lee Grotz, Ian C Munro

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