Obesity and asthma: cause for concern

Current Opinion in Pharmacology
Stephanie A Shore

Abstract

Epidemiological data indicate that obesity is a risk factor for incident asthma, and that obesity is also associated with increased asthma severity. Importantly, obesity antedates asthma. The observations that weight loss improves asthma and that obese mice have innate airway hyperresponsiveness and increased responses to asthma triggers also support a relationship between obesity and asthma. The basis for this relationship is unknown, but might be the result of common etiologies, comorbidities, effects of obesity on lung volume or adipokines. Understanding the mechanistic basis for the relationship between obesity and asthma could lead to new therapeutic strategies for treatment of this susceptible population.

Citations

Jun 30, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Shilpa DograChris I Ardern
Sep 11, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Tim J T SutherlandRobert J Hancox
Jun 4, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Stanislav HenkinXiang Gao
May 12, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Mandana ArshiClaire Wainwright
Jan 1, 2008·Lung India : Official Organ of Indian Chest Society·Pr Gupta
Apr 5, 2011·Archivos de bronconeumología·Claudio RabecDaniel Veale
Jul 26, 2011·The Journal of Allergy and Clinical Immunology·Anne E DixonCharles G Irvin
Dec 6, 2008·Nutrition·Xiaojing LiuFengming Luo
Nov 19, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S FitzpatrickJ I Silverberg
Apr 21, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D Gibeon, K F Chung
Jun 2, 2012·Economics and Human Biology·Barbara H FieseDiana Grigsby-Toussaint
Nov 30, 2006·Current Opinion in Pulmonary Medicine·Stephanie A Shore
Jun 28, 2007·Pediatric Pulmonology·Diletta de Benedictis, Andrew Bush
Oct 21, 2006·Journal of Applied Physiology·Stephanie A Shore
Dec 21, 2019·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Elaine Cristina Caon de SouzaEmilio Pizzichini
Oct 13, 2011·The Journal of Pharmacy and Pharmacology·Li-hui LongJing Liu
Feb 23, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Juan Luis Rodriguez HermosaJose Luis Alvarez-Sala Walther
Feb 1, 2011·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Luísa L BarrosAlvaro A Cruz
Nov 6, 2007·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Aline Petter SchneiderCarlos Cezar Fritscher
Jun 22, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Leslie C GrammerLaura S Sadowski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.