Abstract
Background: obesity and associated cardiometabolic complications are increasing among adults with cerebral palsy (CP). Information in children is scarce, and there is no consensus definition of obesity. Objectives: to describe the frequency of obesity and metabolic complications in children and adolescents with CP. Methods: a descriptive, cross-sectional study performed in two outpatient pediatric special needs centers. Demographic, anthropometric (Brooks 2011), and motor function (GMFCS) data, as well as antiepileptic use, were recorded. Fasting triglycerides (TG), total cholesterol (TC), vitamin D (25OHD), glycemia (GLY), and insulinemia levels were measured. The HOMA index was calculated. Results: sixty-five patients were enrolled. Aage was 10.8 ± 4.9 years; 63.1 % were male; 81.6 % had GMFCS IV-V; 43.5 % had a gastrostomy; and 83.1 % were on antiepileptics. According to their BMI, 15.4 % were underweight (< 10th percentile) and 10.8 % overweight (> 75th percentile). Overall, 6.1 % had TC ≥ 200 mg/dL, 21.4 % had TG ≥ 110 or 130 mg/dL, 4.6 % had GLY ≥ 100 mg/dL, 16.9 % had HOMA ≥ 3, and 76.9 % had 25OHD < 30 ng/mL. Children with BMI ≥ 75th percentile had higher HOMA and insulin resistance rates than those with BMI < 75th perc...Continue Reading
References
Nov 1, 1981·The American Journal of Clinical Nutrition·A R Frisancho
Jun 1, 1995·Archives of Pediatrics & Adolescent Medicine·R D Stevenson
Oct 1, 1996·The American Journal of Clinical Nutrition·V A StallingsE B Charney
Dec 1, 1996·The Journal of Pediatrics·M P AzcueP B Pencharz
Apr 1, 1997·Developmental Medicine and Child Neurology·R PalisanoB Galuppi
Aug 18, 2001·Developmental Medicine and Child Neurology·R M ShavelleS M Day
Jul 3, 2002·Pediatrics·Richard C HendersonRichard D Stevenson
Jan 27, 2007·Developmental Medicine and Child Neurology·David StraussSteven Day
Jul 10, 2008·Developmental Medicine and Child Neurology·David StraussRobert Shavelle
Dec 30, 2008·The Journal of Pediatrics·David L JohnsonChristopher M Modlesky
Oct 9, 2009·Developmental Medicine and Child Neurology·Matthew J GurkaRichard C Henderson
Nov 21, 2009·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Hoda Y TomoumKhadija M Alian
Jan 1, 2010·Research in Developmental Disabilities·Pei-Ying LinJin-Ding Lin
Mar 30, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Elsbeth A C CalisCorine Penning
Jun 17, 2010·Archives of Disease in Childhood·Gillian BairdDiana Elbourne
Oct 23, 2010·Developmental Medicine and Child Neurology·Angharad Vernon-RobertsPeter B Sullivan
Jun 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Michael F HolickUNKNOWN Endocrine Society
Jul 13, 2011·Developmental Medicine and Child Neurology·Lena WestbomEva Nordmark
Jul 20, 2011·Pediatrics·Jordan BrooksDavid Strauss
Nov 16, 2011·Pediatrics·UNKNOWN Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, UNKNOWN National Heart, Lung, and Blood Institute
Apr 5, 2014·Physical Therapy·Jennifer M RyanJohn Gormley
May 28, 2014·Research in Developmental Disabilities·Jennifer M RyanJohn Gormley
Aug 15, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A-K FinbråtenT Vik
Sep 4, 2014·Nutrients·Patricia G WeylandJill Howie-Esquivel
Apr 2, 2015·Developmental Medicine and Child Neurology·Ane-Kristine FinbråtenTorstein Vik
Apr 4, 2015·PloS One·Jennifer M RyanJohn Gormley
May 20, 2015·Epilepsy Research·Manav V VyasJorge G Burneo
Dec 31, 2015·Childhood Obesity·Amy C McPhersonUNKNOWN DOCC-Net (Disability and Obesity in Canadian Children Network)
Jan 14, 2016·Data in Brief·P G McPheeM J MacDonald
Oct 30, 2016·Epilepsy Research·Yoshiaki YamamotoYushi Inoue
Sep 13, 2017·Revista chilena de pediatría·M J FigueroaS Barja
Mar 8, 2018·Developmental Medicine and Child Neurology·Ibrahim DuranEckhard Schoenau
Mar 25, 2018·Developmental Medicine and Child Neurology·Jennifer M RyanMark D Peterson
Mar 25, 2019·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Koen HuysentruytJean De Schepper