Obesity and dyslipidemia in patients with psoriasis: A case-control study

Medicine
Chaoyang MiaoXiaoyan Zhang

Abstract

The aim of this study was to conduct a more comprehensive analysis of the association between psoriasis and abnormal lipid metabolism.The case-control study included 222 psoriatic patients and 445 non-psoriatic control patients matched for age and gender. Clinical parameters included age, gender, and body mass index (BMI). Serum lipid levels were recorded and included cholesterol (CHO), triglycerides (TG), low-density lipoprotein (LDL), high density lipoprotein (HDL), phospholipids (PLIP), free fatty acids (FFA), lipoprotein (a) [Lp(a)], and apolipoproteins (apoA1, apoB, and apoE). Statistical analysis was carried out through the IBM Statistical Package for the Social Studies version 23.0.Compared with controls, levels of BMI and the prevalence of obesity were significantly higher in psoriatic patients. The results revealed that when compared to controls, significant elevation of serum TG (P <.001) and Lp(a) (P = .022) was observed. Levels of HDL (P <.001) and apoA1 (P <.001) were significantly lower in psoriatic patients. There was no significant difference in CHO (P = .367), LDL (P = .400), apoB (P = .294), apoE (P = .05), PLIP (P = .931) and FFA (P = .554) between patients and controls. The levels of CHO, TG, PLIP, FFA, and ...Continue Reading

References

Jan 1, 1975·Dermatologica·S BrennerI Tamir
Oct 1, 1992·Diabetes·K R Feingold, C Grunfeld
May 1, 1989·Endocrinology·K R FeingoldC Grunfeld
Jan 1, 1985·Archives of Dermatological Research·C VahlquistB Vessby
Jan 1, 1984·Acta Neuropathologica·J TanakaK Takahashi
Nov 1, 1994·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·K R FeingoldC Grunfeld
Feb 13, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·P Rocha-PereiraF Teixeira
Mar 21, 2006·Journal of the American Academy of Dermatology·Lotus MallbrisMona Ståhle
Aug 19, 2007·Archives of Internal Medicine·Arathi R SettyHyon K Choi
Jan 25, 2008·Dermatology : International Journal for Clinical and Investigative Dermatology·A D CohenJ Meyerovitch
Jul 22, 2008·The British Journal of Dermatology·J DreiherA D Cohen
Sep 9, 2008·Endocrinology and Metabolism Clinics of North America·Guenther Boden
Mar 31, 2009·Cell Biochemistry and Function·Aysun TokerFatih Akçay
Apr 2, 2009·International Journal of Dermatology·Aldona PietrzakTorello Lotti
Jun 6, 2009·Archives of Dermatological Research·Anthony KarpouzisStavroula Vouliana Veletza
Feb 20, 2010·Acta Dermato-venereologica·Matthias AugustinMarc Radtke
Jul 9, 2011·European Journal of Dermatology : EJD·Christine WarneckeWiebke K Peitsch
Nov 25, 2011·The Journal of Investigative Dermatology·Sinéad M LanganJoel M Gelfand
Dec 30, 2011·Current Pharmaceutical Design·Gerasimos SiasosAthanasios G Papavassiliou
Jul 28, 2012·The British Journal of Dermatology·M AsefiT Pourmotabbed
Oct 31, 2012·The British Journal of Dermatology·C MaA W Armstrong
Nov 5, 2013·Mayo Clinic Proceedings·Terry A Jacobson
Nov 29, 2013·Annals of the Rheumatic Diseases·Klaus W FrommerElena Neumann
Jul 24, 2015·Dermatology : International Journal for Clinical and Investigative Dermatology·Arnd JacobiMarc A Radtke
May 24, 2016·European Journal of Immunology·Kristin StelznerAnja Saalbach
Aug 12, 2016·Disaster Medicine and Public Health Preparedness·Megan PeckDebra K Olson
Oct 26, 2016·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·M BucciF Cipollone
Feb 19, 2017·Archives of Dermatological Research·Line RaabyAnnette de Thurah
Sep 25, 2017·Journal of Diabetes·Zachary Bloomgarden, Guang Ning

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Methods Mentioned

BETA
PLIP

Software Mentioned

Statistical Package for the Social Studies

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