PMID: 15384801Sep 24, 2004Paper

Obesity and patient survival in chronic dialysis

Advances in Peritoneal Dialysis
Antonios H Tzamaloukas, Glen H Murata

Abstract

Obesity shortens survival in the general population. In hemodialysis (HD), obesity is associated with improved short-term survival (around 3 years). The discrepancy in the survival of obese patients between HD and the general population may be attributable to survival bias. (Only a small percentage of patients with renal failure survive until HD, and they may have certain survival advantages, including obesity.) Bias is introduced through the mixture of prevalent and incident HD patients in most studies, better nutrition in obese HD patients, malnutrition-inflammation complex syndrome causing weight loss, or other reasons. In studies of peritoneal dialysis (PD), obesity has been associated with decreased patient survival, no noticeable effect on survival, and increased survival. Potential reasons for the differences include bias in the selection of PD for obese patients, effects of race, chronic inflammation in obese PD patients, differences in nutrition and adequacy of PD, adverse effects of the increased PD dose needed to achieve adequate small-solute clearances, differences in body composition, and time discrepancies among risk factors having opposite effects on PD patient survival. Some evidence exists that in the long-term...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Clinical Nutrition
Kamyar Kalantar-ZadehTamara Horwich
Journal of the American College of Cardiology
Kamyar Kalantar-ZadehGregg C Fonarow
Advances in Peritoneal Dialysis
Rajesh Yalavarthy, Isaac Teitelbaum
© 2021 Meta ULC. All rights reserved