Obesity is a major risk factor for prosthetic infection after primary hip arthroplasty

Clinical Orthopaedics and Related Research
Michelle M Dowsey, Peter F M Choong

Abstract

The incidence of obesity and the number of hip arthroplasties being performed in Australia each year are increasing. Although uncommon, periprosthetic infection after surgery can have a devastating effect on patient outcomes. We therefore asked whether obesity correlated with periprosthetic infection after primary hip arthroplasty. We further asked whether variables such as patient comorbidities, operative time, blood transfusions, use of drains, and cementation practices correlated with periprosthetic infection. We hypothesized obesity was an independent risk factor for the development of acute periprosthetic infection after primary hip arthroplasty. We reviewed 1207 consecutive primary hip arthroplasties separating patients into four weight groups, normal, overweight, obese, and morbidly obese, and compared for incidence of periprosthetic infection between the groups. We observed a considerably higher infection rate in obese patients; the correlation was independent of patient comorbidities such as diabetes and cardiovascular disease. We also observed a correlation between infection rates and using a posterior approach in obese patients. The incidence of periprosthetic infection was not influenced by operative time, transfusi...Continue Reading

References

Sep 16, 1991·The American Journal of Medicine·R A GaribaldiT Lerer
Jan 1, 1989·The Journal of Bone and Joint Surgery. British Volume·A S Baker, V C Bitounis
Jun 1, 1994·The Journal of Bone and Joint Surgery. American Volume·D E LehmanJ R Feinberg
Nov 1, 1996·The Journal of Bone and Joint Surgery. British Volume·A E WealeG C Bannister
Apr 1, 1998·American Journal of Epidemiology·C CooperD Coggon
Apr 29, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·A J MangramW R Jarvis
Apr 27, 2001·Obesity Research·B SticklesW L Lanzer
Mar 7, 2002·Arthritis Research·Ray Marks, John P Allegrante
Jun 1, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Khaled SalehEdward McElfresh
Feb 15, 2003·The American Journal of Medicine·Elizabeth W KarlsonFrancine Grodstein
Apr 30, 2004·The Medical Journal of Australia·Joseph Proietto, Louise A Baur
Jun 3, 2005·Clinical Orthopaedics and Related Research·Nitin B JainLaurence D Higgins
Sep 29, 2005·The Journal of Bone and Joint Surgery. British Volume·P J WalmsleyI Brenkel
Oct 11, 2005·The Journal of Arthroplasty·Robert S NambaMary Lou Stone
Oct 19, 2005·The Journal of Arthroplasty·Matthew MoranI J Brenkel
Aug 10, 2006·Surgical Infections·Antonio Sitges-SerraEstela Membrilla
Oct 3, 2006·The Journal of Bone and Joint Surgery. British Volume·F Horan
Oct 3, 2006·The Journal of Bone and Joint Surgery. British Volume·J R McLaughlin, K R Lee

❮ Previous
Next ❯

Citations

Jun 1, 2010·International Orthopaedics·Eric YeungWilliam Walter
Mar 15, 2012·The Proceedings of the Nutrition Society·J Justin Milner, Melinda A Beck
Aug 21, 2009·The New England Journal of Medicine·Jose L Del Pozo, Robin Patel
Sep 21, 2012·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Alexandre RenaudPascal-André Vendittoli
Sep 2, 2011·Acta chirurgica Iugoslavica·Cedomir VucetićZoran Vukasinović
Sep 12, 2013·World Journal of Gastroenterology : WJG·Antonella ScaleraGiovanni Tarantino
Jan 7, 2016·The Bone & Joint Journal·K I Perry, S J MacDonald
Apr 1, 2014·Orthopedics·Patrick KaneAlvin Ong
Jun 1, 2013·The Bone & Joint Journal·R RajgopalR Bourne
Jun 16, 2015·TheScientificWorldJournal·Georgios TriantafyllopoulosLazaros A Poultsides
Oct 3, 2014·The Bone & Joint Journal·R LargeD I Clark
Oct 21, 2016·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Svetlana BozhkovaAnna Rukina
Jan 10, 2016·Foot & Ankle International·Matthew S StewartElizabeth A Tolley
Sep 23, 2016·The Journal of Bone and Joint Surgery. American Volume·Joshua S EverhartStanley Lemeshow
Apr 4, 2017·The Journal of Arthroplasty·Noam Shohat, Javad Parvizi
May 9, 2014·Expert Review of Anti-infective Therapy·Kenna D Payne, Ronald G Hall
Mar 10, 2017·European Journal of Medical Research·Heinrich M L MühlhoferJohannes Schauwecker
Mar 8, 2017·Current Diabetes Reports·Funke Akiboye, Gerry Rayman
Dec 22, 2016·Cirugia y cirujanos·Rafael Franco-CendejasArturo Galindo-Fraga
Feb 21, 2018·The Journal of Bone and Joint Surgery. American Volume·Joshua S EverhartThomas J Scharschmidt
Dec 17, 2017·Lasers in Medical Science·Timothy BriggsMelanie Coathup
May 8, 2018·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Usha GurunathanRoss W Crawford
Oct 3, 2017·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Ryan E HaroldDavid Manning
Dec 4, 2014·Arthritis Care & Research·T N PeelM M Dowsey
Apr 4, 2014·Clinical Microbiology Reviews·Aaron J Tande, Robin Patel
Sep 3, 2010·The Journal of Rheumatology·Til Stürmer, Klaus-Peter Günther
Oct 1, 2008·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Gladius Lewis
Oct 9, 2008·Clinical Orthopaedics and Related Research·Michelle M Dowsey, Peter F M Choong
Apr 10, 2010·Obesity·Rajiv GandhiNizar N Mahomed
Jul 31, 2013·The Open Orthopaedics Journal·Alfonso Del Arco, María Luisa Bertrand
Oct 18, 2013·The Journal of Bone and Joint Surgery. American Volume·Benjamin ZmistowskiJavad Parvizi
Apr 22, 2015·Der Orthopäde·M StiehlerK-P Günther
Dec 2, 2009·The Journal of Bone and Joint Surgery. British Volume·P F M ChoongD Liew
Aug 15, 2015·International Orthopaedics·Zhongxi MaJinming Zhang
Feb 9, 2011·ANZ Journal of Surgery·Trisha N PeelPeter F M Choong
Jan 21, 2012·Transplant Infectious Disease : an Official Journal of the Transplantation Society·P VergidisR R Razonable
Apr 20, 2012·Expert Review of Anti-infective Therapy·Benjamin Zmistowski, Javad Parvizi

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