Obesity is a risk factor for failure of "fast track" extubation following coronary artery bypass surgery

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
Joel L ParlowBrian Milne

Abstract

Obesity is a common comorbid condition among patients undergoing coronary bypass surgery. Previous studies have shown inconsistent results as to whether obese patients require prolonged ventilation after cardiac surgery. Fast track recovery strategies have become common to reduce the duration of ventilation and intensive care. The purpose of this study was to determine whether, in our practice, obesity affects post-operative ventilation time using a fast track recovery strategy. A retrospective continuous quality improvement audit of 200 patient records was performed. Patients were divided into Obese and Non-obese groups using a definition for obesity of body mass index >or= 30.0. Failure of fast track extubation was defined as intubation > six hours. Eighty-four (42.4%) of the patients audited met criteria for obesity. Although most patients successfully underwent fast track recovery, time to extubation was prolonged, and failure of fast track extubation was more common, in obese patients (63% Non-obese vs 46% Obese extubated in < two hours, 98% Non-obese and 85% Obese patients extubated in < six hours, P < 0.001). Increased body mass index, duration of operative time and postoperative serum creatinine were risk factors for fa...Continue Reading

References

Jun 1, 1996·The Annals of Thoracic Surgery·T S Kurki, M Kataja
Mar 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J HerlitzW Sandén
Jul 17, 1999·Heart & Lung : the Journal of Critical Care·C B Sabourin, M Funk
May 10, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·M BrandtJ Cremer
Jun 6, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J ReisM Guerreiro
Nov 29, 2002·Anesthesia and Analgesia·A- S EichenbergerL Magnusson
Jan 2, 2003·Journal of Endocrinological Investigation·G De Pergola, N Pannacciulli
Sep 10, 2003·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Louise K BowlesPeter K MacCallum

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Citations

Sep 7, 2012·Interactive Cardiovascular and Thoracic Surgery·Marco C HaanschotenMohamed A Soliman Hamad
Sep 30, 2008·Thorax·A Malhotra, D Hillman
Jan 30, 2010·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Joel ParlowRachel Phelan
Jun 2, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Constance G WeismannAlexander J C Mittnacht
May 16, 2007·Radiologic Clinics of North America·Raul N Uppot
Jul 19, 2015·American Journal of Obstetrics and Gynecology·Andrew ZakhariHaim A Abenhaim
Sep 7, 2016·The Annals of Thoracic Surgery·Kevin W LobdellJuan A Sanchez
Aug 18, 2016·Journal of Intensive Care Medicine·Telma C A SequeiraAntonio M Esquinas
Jul 15, 2015·Journal of the American Heart Association·Ana P JohnsonBrian Milne
Jun 24, 2008·Expert Review of Cardiovascular Therapy·Pasquale Totaro

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