Obesity management in the liver transplant recipient: the role of bariatric surgery

Current Opinion in Organ Transplantation
Keisha Bonner, Julie K Heimbach

Abstract

The epidemic of obesity is having a marked impact on liver transplant candidates and recipients, and optimal approach for the obese liver transplant patient is not yet defined. The current review summarizes the role of bariatric surgery in obese liver transplant patients. NASH is now the second most common indication for listing for liver transplantation and is the third most common reason for patients undergoing liver transplantation. Recent reports of outcomes for obese recipients demonstrate satisfactory patient and graft survival, though complication rates may be higher. The impact of weight loss on long-term health in the nontransplant population, including those with liver disease, has been demonstrated, though less in known on the impact for weight loss and bariatric surgery for liver transplant recipients. Obesity-related liver disease has become one of the most common indications for liver transplantation and further research is needed to determine the role of bariatric surgery in the optimal management of this population.

References

Jan 12, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Satheesh NairPaul J Thuluvath
Dec 24, 2004·The New England Journal of Medicine·Lars SjöströmUNKNOWN Swedish Obese Subjects Study Scientific Group
Dec 19, 2006·Transplantation Proceedings·T FujikawaA I Reed
Nov 30, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Shawn J PelletierRobert M Merion
Feb 26, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J LeonardM Charlton
Feb 26, 2008·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Mark C TakataAndrew M Posselt
Oct 25, 2008·Annals of Surgery·Dorry L SegevWarren R Maley
Jul 31, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·André A S DickJames D Perkins
Oct 31, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Satheesh NairJames D Eason
Mar 9, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Mustafa S AschaNizar N Zein
May 22, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K D S WattM R Charlton
Jul 30, 2010·Current Medical Research and Opinion·A SanyalV Barghout
Jun 21, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Neeraj BhalaJacob George
Jul 26, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jeffrey D Mosko, Geoffrey C Nguyen
Jun 15, 2012·Clinical Transplantation·John C LaMattinaJoshua D Mezrich
Jun 29, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Deepa T Patil, Lisa M Yerian
Sep 12, 2012·Annals of Surgery·Vatche G AgopianRonald W Busuttil
Nov 10, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J K HeimbachJ M Swain
Dec 4, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Lorenzo A OrciChristian Toso
Feb 2, 2013·Transplantation·Ashwani K SingalRussell H Wiesner
Feb 15, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Abdul R HakeemKrishna V Menon
May 25, 2013·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Matthew Y C LinAndrew M Posselt
Jun 8, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Silvia E Perez-ProttoCharles Miller
Sep 17, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Abdl-Rawf Al-NowaylatiDaniel B Leslie
Sep 18, 2013·Nature Reviews. Gastroenterology & Hepatology·Rohit Loomba, Arun J Sanyal
Apr 14, 2015·Gastroenterology·Eduardo Vilar-GomezManuel Romero-Gomez
Apr 17, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Lynn A FussnerKymberly D Watt
Jun 7, 2015·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Jad KhorakiGuilherme M Campos
Nov 22, 2015·Journal of Gastroenterology and Hepatology·Leon A AdamsUNKNOWN Australian New Zealand Liver Transplant Study Group
Jan 30, 2016·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Enrique F ElliJose Oberholzer
Apr 12, 2016·Clinics in Liver Disease·Tuan PhamMichael R Charlton
Sep 28, 2016·International Journal of Surgery Case Reports·Laura TariciottiGiuseppe Tisone
Feb 16, 2017·The New England Journal of Medicine·Philip R SchauerUNKNOWN STAMPEDE Investigators
Jul 29, 2017·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mohamed SafwanReena Salgia
Aug 5, 2017·Obesity Surgery·Michael OsseisDaniel Azoulay
Jan 4, 2018·The New England Journal of Medicine·Ted D AdamsSteven C Hunt
Jan 6, 2018·The New England Journal of Medicine·Nagaraju Sarabu

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Citations

Jul 21, 2020·Expert Review of Gastroenterology & Hepatology·Nicholas Hoppmann, Omar Massoud
Jun 17, 2019·Current Gastroenterology Reports·Kelly E Diaz, Thomas D Schiano
Dec 20, 2020·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Lokesh AgarwalSandeep Aggarwal
Jun 5, 2021·Cirugía española·Ricard CorcellesMatthew Kroh
Jun 16, 2021·Seminars in Liver Disease·Kathy M Nilles, Josh Levitsky
Jul 3, 2021·Cirugia Española·Ricard CorcellesMatthew Kroh

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