Obesity-related non-communicable diseases: South Asians vs White Caucasians

International Journal of Obesity : Journal of the International Association for the Study of Obesity
A Misra, L Khurana

Abstract

South Asians are at higher risk than White Caucasians for the development of obesity and obesity-related non-communicable diseases (OR-NCDs), including insulin resistance, the metabolic syndrome, type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). Rapid nutrition and lifestyle transitions have contributed to acceleration of OR-NCDs in South Asians. Differences in determinants and associated factors for OR-NCDs between South Asians and White Caucasians include body phenotype (high body fat, high truncal, subcutaneous and intra-abdominal fat, and low muscle mass), biochemical parameters (hyperinsulinemia, hyperglycemia, dyslipidemia, hyperleptinemia, low levels of adiponectin and high levels of C-reactive protein), procoagulant state and endothelial dysfunction. Higher prevalence, earlier onset and increased complications of T2DM and CHD are often seen at lower levels of body mass index (BMI) and waist circumference (WC) in South Asians than White Caucasians. In view of these data, lower cut-offs for obesity and abdominal obesity have been advocated for Asian Indians (BMI; overweight >23 to 24.9 kg m(-2) and obesity ≥ 25 kg m(-2); and WC; men ≥ 90 cm and women ≥ 80 cm, respectively). Imbalanced nutrition, physical i...Continue Reading

References

Aug 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·A C BurdenJ Walls
Jul 1, 1989·BMJ : British Medical Journal·A SamantaA C Burden
Aug 26, 1989·BMJ : British Medical Journal·L O HughesE B Raftery
Jan 1, 1989·Journal of Clinical Epidemiology·P M McKeigueM G Marmot
Oct 19, 1989·The New England Journal of Medicine·C C CowieV M Hawthorne
Nov 1, 1988·British Heart Journal·P M McKeigueR A Riemersma
Sep 3, 1988·BMJ : British Medical Journal·A RamachandranM Viswanathan
Oct 8, 1988·BMJ : British Medical Journal·P M McKeigue, M G Marmot
Nov 1, 1987·Diabetes Research and Clinical Practice·A SamantaB Fent
Oct 1, 1986·Journal of Clinical and Hospital Pharmacy·M Aslam, M A Healy
May 18, 1985·British Medical Journal·R E Lawrence, W A Littler
Oct 19, 1985·British Medical Journal·H M Mather, H Keen
Jul 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·C F CloseM Nattrass
Feb 1, 1995·British Heart Journal·H T Mukhtar, W A Littler
Sep 1, 1994·Postgraduate Medical Journal·J Dhawan, C L Bray
Feb 1, 1994·International Journal of Epidemiology·R WilliamsK Hunt
Apr 1, 1993·Journal of Epidemiology and Community Health·T KnightM R Baker
Jan 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·K HawthorneS Tomlinson
Apr 1, 1993·Diabetic Medicine : a Journal of the British Diabetic Association·J S GujralA C Burden
Apr 1, 1997·Arteriosclerosis, Thrombosis, and Vascular Biology·T J AitmanJ Scott
Mar 8, 1997·BMJ : British Medical Journal·S Wild, P McKeigue
May 17, 1997·BMJ : British Medical Journal·K Hawthorne
Mar 1, 1997·Ethnicity & Health·K J Wrightson, J Wardle

❮ Previous
Next ❯

Citations

Mar 13, 2012·Journal of Immigrant and Minority Health·Eivind AndersenSigmund A Anderssen
Feb 23, 2012·Current Diabetes Reports·Shashank R JoshiAlbert Marchetti
Apr 25, 2013·European Journal of Clinical Nutrition·S M ChopraR Gupta
Aug 25, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A ShahA M Kanaya
Aug 5, 2011·Journal of Human Genetics·Ganesh ChauhanDwaipayan Bharadwaj
Aug 3, 2012·Diabetes Technology & Therapeutics·Ritesh Gupta, Anoop Misra
May 21, 2013·Metabolic Syndrome and Related Disorders·Christine P StewartKeith P West
Nov 19, 2011·International Journal of Evidence-based Healthcare·Ritin FernandezBronwyn Everett
Jun 9, 2012·Lipids in Health and Disease·Gabriela T D SousaGustavo D Pimentel
Jul 19, 2013·Nutrients·Anoop Misra, Usha Shrivastava
Aug 8, 2012·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Rohini MathurJohn Robson
Nov 10, 2012·Food & Nutrition Research·Gerd Holmboe-Ottesen, Margareta Wandel
Jul 28, 2012·Indian Journal of Endocrinology and Metabolism·Senthil K Vasan, Nihal Thomas
Jan 26, 2012·Indian Journal of Endocrinology and Metabolism·Kaushik PanditSubhankar Chowdhury
Sep 13, 2013·Journal of Cardiovascular Disease Research·D S PrasadB C Das
Jul 23, 2013·Archives of Gynecology and Obstetrics·K G ParhoferA W Flemmer
Jul 23, 2014·BioMed Research International·Anna Yermachenko, Volodymyr Dvornyk
Nov 28, 2013·Journal of Community Health·Robert J WongAijaz Ahmed
Apr 23, 2014·Diabetes Technology & Therapeutics·Usha Shrivastava, Anoop Misra
Aug 6, 2013·International Journal of Epidemiology·Shu-E SohUNKNOWN GUSTO Study Group
Nov 6, 2014·Journal of Nutrition and Metabolism·Sharma SowmyaSambashivaiah Sucharita
May 29, 2013·Nutrition & Diabetes·S KalraS S Anand
Sep 13, 2012·Journal of Immigrant and Minority Health·Kristen M J AzarLatha P Palaniappan
Jan 1, 2013·Current Cardiovascular Risk Reports·Gita Wahi, Sonia S Anand
Jan 18, 2015·Indian Heart Journal·K Sarat ChandraSeema Gulati
Nov 22, 2015·Cancer Causes & Control : CCC·Rajini NagraniRajesh Dikshit
Jan 10, 2013·Diabetes Research and Clinical Practice·R JayawardanaP Katulanda
May 29, 2015·Journal of Diabetes·Usha ShrivastavaVijay Viswanathan
Mar 5, 2016·Diabetes Technology & Therapeutics·Subhash Kumar Wangnoo
Oct 27, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A D ShahA M Kanaya
Mar 13, 2016·Journal of Immigrant and Minority Health·Pamela Martyn-NemethGrishma Shah
Sep 10, 2014·Paediatrics and International Child Health·E M E Poskitt
Sep 5, 2012·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·S D Garduño-Diaz, S Khokhar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.

Antipsychotic-Induced Weight Gain

Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.