Abstract
The National Bariatric Surgery Registry (NBSR) is the largest bespoke database in the field in the United Kingdom. Our aim was to analyze the NBSR to determine whether the effects of obesity surgery on associated co-morbidities observed in small randomized controlled clinical trials could be replicated in a "real life" setting within U.K. healthcare. United Kingdom. All NBSR entries for operations between 2000 and 2015 with associated demographic and co-morbidity data were analyzed retrospectively. A total of 50,782 entries were analyzed. The patients were predominantly female (78%) and white European with a mean age of 45 ± 11 years and a mean body mass index of 48 ± 8 kg/m2. Over 5 years of follow-up, statistically significant reductions in the prevalence of type 2 diabetes, hypertension, dyslipidemia, sleep apnea, asthma, functional impairment, arthritis, and gastroesophageal reflux disease were observed. The "remission" of these co-morbidities was evident 1 year postoperatively and reached a plateau 2 to 5 years after surgery. Obesity surgery was particularly effective on functional impairment and diabetes, almost doubling the proportion of patients able to climb 3 flights of stairs and halving the proportion of patients wi...Continue Reading
Citations
Oct 28, 2019·Obesity Surgery·Mahmoud AlmustafaAiman Suleiman
Jan 23, 2020·The British Journal of Surgery·P SinghA A Tahrani
Dec 12, 2019·Obesity Surgery·Shulamit GellerSubhi Abu-Abeid
Feb 9, 2020·BMJ Open·Karen D CoulmanAmanda Owen-Smith
Jul 5, 2018·BMJ Sexual & Reproductive Health·Yitka N H GrahamIan S Fraser
Jun 2, 2018·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Roxanna Zakeri, Rachel L Batterham
Aug 9, 2019·Surgical Endoscopy·Anna KamockaAhmed Rashid Ahmed
Dec 1, 2018·Visceral Medicine·Anne-Catherine SchwarzBeat P Müller-Stich
Dec 1, 2019·Diabetic Medicine : a Journal of the British Diabetic Association·A MaulaD Kendrick
Jul 30, 2018·Obesity Surgery·Muhammad Qutayba AlmeriePrashant Jain
Jul 30, 2020·PLoS Medicine·Tom WigginsSheraz R Markar
Dec 8, 2020·PLoS Medicine·Emma Rose McGloneOmar A Khan
Mar 4, 2021·Nutrients·Dimitris Papamargaritis, Carel W le Roux
Apr 14, 2021·Obesity Surgery·Irena StefanovaChristopher Pring
Dec 24, 2019·Revue des maladies respiratoires·T Villeneuve, L Guilleminault
Jul 1, 2021·Annals of the Royal College of Surgeons of England·R MamidannaO Al-Taan
Jul 17, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Anna KamockaUNKNOWN NBSR Committee
Jul 24, 2021·The British Journal of Surgery·A G N RobertsonR Welbourn
Oct 27, 2021·The Journal of Clinical Endocrinology and Metabolism·Stephanie GriggsRonald L Hickman