Obesity with abundant subcutaneous adipose tissue increases the risk of post-ERCP pancreatitis

Journal of Gastroenterology
Toshio FujisawaNobuyuki Matsuhashi

Abstract

The risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) have been widely investigated. However, studies focusing on the body mass index (BMI) and distribution of adipose tissue have not been reported. Therefore, we examined the correlation between PEP and these factors. A total of 583 consecutive endoscopic retrograde cholangiopancreatography (ERCP)-naïve patients undergoing therapeutic ERCP were retrospectively analyzed. Subjects were categorized into four groups by BMI: underweight, normal, overweight, and obesity; the PEP rates were compared. In addition, the relationship between PEP and parameters of obesity, visceral and subcutaneous adipose tissue as well as abdominal circumference was investigated. PEP rate was significantly higher in obesity (30 %) and lower in normal (3 %, P < 0.001). The PEP rate in underweight (7.3 %) was conversely higher than in normal. As for parameters of obesity, only subcutaneous adipose tissue was correlated with PEP incidence (P = 0.009). The correlation of PEP incidence with BMI and subcutaneous adipose tissue was separately reconfirmed by multivariate analysis including female gender and guidewire placement; these factors showed a tendency toward differen...Continue Reading

References

Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Jun 3, 2004·Gastrointestinal Endoscopy·Martin L Freeman, Nalini M Guda
Nov 24, 2004·Gastrointestinal Endoscopy·Merete ChristensenJacob Rosenberg
May 19, 2007·The American Journal of Gastroenterology·Angelo AndriulliRosario Forlano
Oct 22, 2008·Journal of Clinical Gastroenterology·Viju P DeenadayaluStuart Sherman
Dec 9, 2008·The Journal of Surgical Research·Terence E WadeNicholas J Zyromski
Mar 17, 2009·Gastrointestinal Endoscopy·Peter B CottonJoseph Romagnuolo
Jul 21, 2009·The Journal of Biological Chemistry·Eduardo J FolcoPeter Libby
Nov 13, 2009·World Journal of Gastroenterology : WJG·Jean-Louis FrossardCatherine M Pastor
Dec 17, 2009·Journal of Hepato-biliary-pancreatic Sciences·Shinju ArataMasao Tanaka
Mar 2, 2010·Gastrointestinal Endoscopy·Peter B CottonJohn J Vargo
May 28, 2010·Endoscopy·J-M DumonceauUNKNOWN European Society of Gastrointestinal Endoscopy
Aug 2, 2011·Journal of Gastroenterology·Yoko YashimaMasao Omata
Sep 10, 2011·European Journal of Gastroenterology & Hepatology·Shen HongTong Chaoyang
Feb 22, 2012·Gastrointestinal Endoscopy·Michelle A AndersonJason A Dominitz
Jan 29, 2013·Cell Metabolism·Toshimasa Yamauchi, Takashi Kadowaki
Feb 14, 2013·International Journal of Cancer. Journal International Du Cancer·Xiao-Feng DuanZhen-Tao Yu
Dec 3, 2014·Gastrointestinal Endoscopy·Yousuke NakaiKazuhiko Koike
May 27, 2015·Archives of Medical Research·María Luna-LunaÓscar Pérez-Méndez
Jun 2, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·N TewariD N Lobo
Oct 21, 2015·The American Journal of Gastroenterology·Somashekar G KrishnaDarwin L Conwell

❮ Previous
Next ❯

Citations

Oct 18, 2016·Gastroenterología y hepatología·Antonio López-SerranoEduardo Moreno-Osset
Jan 3, 2020·Journal of Clinical Gastroenterology·Ryunosuke HakutaKazuhiko Koike
Jul 3, 2021·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Ko TomishimaHiroyuki Isayama

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.