Objective and quantitative evaluation of angiographic vascularity in meningioma: parameters of dynamic susceptibility contrast-perfusion-weighted imaging as clinical indicators of preoperative embolization.

Neurosurgical Review
Kazuhide AdachiYuichi Hirose

Abstract

Digital subtraction angiography (DSA) assesses the necessity of preoperative embolization in meningioma cases but entails complication risks. Previous studies evaluating meningiomas' angiographic vascularity using perfusion-weighted imaging (PWI) have performed subjective visual assessments, not managing to assess the need for preoperative embolization. We objectively assessed the angiographic stain of meningiomas and examined the usefulness of two parameters of dynamic susceptibility contrast (DSC)-PWI, normalized cerebral blood volume (nCBV) and cerebral blood flow (nCBF), in predicting vascularity and the necessity of preoperative embolization. We retrospectively examined 52 patients who underwent surgery for primary meningioma and preoperative DSA and DSC-PWI. We calculated the normalized luminance (nLum) of the tumor stain in DSA. In 29 meningioma cases with a single feeding artery, we determined the DSC-PWI parameter that correlated with meningioma angiographic vascularity and predicted the necessity of preoperative embolization. We also compared vascularity between meningiomas with single and multiple feeding arteries and between convexity and skull-base meningiomas. nCBF (cut off: 3.66, P = 0.03, area under the curve [A...Continue Reading

References

Jun 3, 1999·Radiology·E A KnoppI I Kricheff
Jun 11, 2008·Neuroradiology·Hao ZhangMatthijs Oudkerk
Apr 12, 2014·AJNR. American Journal of Neuroradiology·D M S RaperK C Liu
Sep 12, 2015·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Kazuhide AdachiMitsuhiro Hasegawa
May 18, 2016·World Neurosurgery·Kazuhide AdachiYuichi Hirose
Jun 6, 2017·Neurologia Medico-chirurgica·Kazuhide AdachiYuichi Hirose

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Citations

Jun 21, 2021·Seminars in Ultrasound, CT, and MR·Claudia F Kirsch, Mai-Lan Ho

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