Objective measures of sleepiness and wakefulness: application to the real world?

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
Merrill S Wise

Abstract

The impact of excessive sleepiness on the individual and on society is immense, and chronic sleepiness is one of the most common complaints evaluated by sleep medicine specialists. The author explores how measures of sleepiness and wakefulness using the Multiple Sleep Latency Test (MSLT) and the Maintenance of Wakefulness Test (MWT) can be clinically useful. A companion article presents a counterpoint discussion of the limitations and drawbacks associated with the MSLT and MWT. Both presentations use an evidence-based approach to understanding the operating characteristics of these tests, and the overall goal is to clarify for sleep medicine specialists the positive and negative attributes of the MSLT and MWT. The MSLT and MWT are the most widely accepted objective measures of an individual's ability to fall asleep and ability to remain awake, respectively. The MSLT is a well-validated and extensively published objective measure of the speed at which a subject falls asleep under standardized laboratory conditions, and it is associated with good to excellent interrater and intrarater reliability, and excellent test-retest reliability. The MSLT is indicated as part of the evaluation of suspected narcolepsy and it may be helpful i...Continue Reading

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