Objective tremor registration during DBS surgery for essential tremor

Clinical Neurology and Neurosurgery
S PapapetropoulosJ R Jagid

Abstract

Essential Tremor (ET) is characterized by a 4-12-Hz postural and kinetic tremor, most commonly affecting the upper limbs. Deep brain stimulation (DBS) of the thalamus (Vim) has been found to be highly effective in severe/refractory forms of ET. Intra-operative assessment of tremor is performed using clinical methods based on patient and physician perception of tremor intensity. We present for the first time the case of a patient whose tremor was objectively monitored/quantified pre- and intra-operatively using device-based tremor registration to supplement clinical measures. We present the case of a 76-year-old right-handed woman that received unilateral (left-sided) DBS of the ventrointermediate (Vim) nucleus of thalamus (Vim) for medically refractory ET. Tremor was monitored with an accelerometer-based Tremor Pen, which is part of a simple portable device (CATSYS 2000 System, Danish Product Development Ltd., DK, www.catsys.dk). The patient was asked to perform tasks for tremor evaluation before and during thalamic DBS. Tremor quantification revealed a significant improvement (34.7-fold) in the contralateral (right) limb following macro-stimulation. No significant improvement was registered in the ipsilateral (non-operated) si...Continue Reading

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Citations

Jun 3, 2010·Medical & Biological Engineering & Computing·Simone Hemm, Karin Wårdell
May 4, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Blake K ScanlonSpiridon Papapetropoulos
Nov 21, 2009·Clinical Neurology and Neurosurgery·Oraporn SitburanaWilliam G Ondo
Jun 9, 2016·Movement Disorders : Official Journal of the Movement Disorder Society·Dietrich HaubenbergerRodger J Elble

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