Jan 1, 1982

Obligatory amino acids in primitive proteins

Bio Systems
A S Kolaskar, V Ramabrahmam


Conformational similarity among amino acid residues, a property derived by analysing (phi, psi)-probability distributions of 20 proteinous amino acids from 38 different globular proteins, is used to arrive at a set of six 'obligatory' amino acids of primitive proteins. The amino acids Ser, Val, Leu, Asp, Gly and Pro have been argued to be 'obligatory' and to represent, conformationally, the remaining amino acids. The reasons for consideration of these six residues as 'obligatory' are discussed. Methods to check the validity of our proposition are suggested.

Mentioned in this Paper

Amino Acids, I.V. solution additive
Gene Products, Protein
Protein Conformation
Amino Acid [EPC]
Origin of Life
Biological Evolution
Antifibrinolytic amino acids

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