Observation of molecular inhibition and binding structures of amyloid peptides

Nanoscale
Chenxuan WangChen Wang

Abstract

Unveiling interactions between labeling molecules and amyloid fibrils is essential to develop new detection methods for studying amyloid structures under various conditions. This review endeavours to reflect the progress in studying interactions between molecular inhibitors and amyloid peptides using a series of experimental approaches, such as X-ray diffraction, nuclear magnetic resonance, scanning probe microscopy, and electron microscopy. The revealed binding mechanisms of anti-amyloid drugs and target proteins could benefit the rational design of drugs for prevention or treatment of amyloidal diseases.

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Citations

Jun 1, 2013·Advanced Materials·Min ZhangChen Wang
May 14, 2016·Physical Chemistry Chemical Physics : PCCP·Huiling ZhaoMingdong Dong
May 7, 2016·ACS Applied Materials & Interfaces·Sayan Roy ChowdhuryParameswar Krishnan Iyer
Jun 30, 2016·ACS Chemical Neuroscience·K RajasekharT Govindaraju
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Apr 5, 2018·The Journal of Biological Chemistry·Stephen BruinsmaThomas F J Martin
Apr 25, 2013·Nanoscale·Xingfei ZhouYi Zhang
Sep 17, 2013·Chemical Communications : Chem Comm·Hongchao MaJunbai Li
Nov 17, 2020·Frontiers in Chemistry·Wenbo ZhangChenxuan Wang
Aug 6, 2021·Frontiers in Bioengineering and Biotechnology·Qize XuanPing Wang
Mar 7, 2017·Chemistry of Materials : a Publication of the American Chemical Society·Shih-Ting WangMolly M Stevens

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