PMID: 6163956Jan 1, 1981Paper

Observation on the capping of spleen lymphocytes from scrapie infected mice after treatment with anti Ig

Medical Microbiology and Immunology
W VettermannM A Koch

Abstract

Staining of lymphocytes from scrapie-infected STU mice with FITC-labelled anti-mouse Ig revealed disturbances in the capping process when compared with lymphocytes from mock-infected animals. Quantitative evaluation indicates that 10-15% of cells from scrapie-infected animals show an altered capping behaviour. These phenomena are discussed with special reference to the role of the lymphoreticular system in early scrapie agent replication.

References

Apr 1, 1969·Journal of Comparative Pathology·A C Gardiner, A A Marucci

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