Observational study of compliance and continuance rates of raloxifene in the prevention and treatment of osteoporosis

Current Therapeutic Research, Clinical and Experimental
José R ZanchettaCarola Lombas

Abstract

Abstract. Medical practitioners face the challenge of noncompliance with prescriptions, particularly in chronic, asymptomatic, diseases such as osteoporosis. The aim of this study was to assess the raloxifene compliance and continuance rates and adverse effects over 24 months in clinical practice. Using a retrospective study of clinical histories obtained from a database at the Metabolic Research Institute, University of El Salvador School of Medicine, Buenos Aires, Argentina, as well as telephone interviews, we assessed compliance and continuance with raloxifene therapy in post-menopausal patients who had received prescriptions for raloxifene to prevent or treat osteoporosis. Patients were contacted by telephone 24 months after they had received a prescription for raloxifene. Compliance and continuance rates were calculated based on the data provided by the patients. Data from 419 patients (mean [SD] age, 61.4 [7.4] years [range, 42-90 years]) were included in the study. At the time of the telephone interview, 225 (53.7%) were still receiving raloxifene, 105 (25.1%) had stopped treatment at their own discretion, 59 (14.1%) had not started treatment, and 30 (7.2%) had discontinued treatment as a result of advice from a physicia...Continue Reading

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Citations

Jun 17, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Jean-Yves ReginsterPierre D Delmas
Oct 18, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J D RingeH Faber
Jan 25, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E SeemanJ A Cramer
May 23, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J FiniganR Eastell
Feb 27, 2007·Journal of Bone and Mineral Metabolism·Ellewellyn G PasionDaniel Thiebaud
Jan 20, 2007·Drugs & Aging·Alexandra PapaioannouJonathan D Adachi
Oct 10, 2013·Current Medical Research and Opinion·Xavier NoguesAlicia López Rodríguez
Sep 5, 2006·Joint, Bone, Spine : Revue Du Rhumatisme·Bernard Cortet, Olivier Bénichou
Sep 28, 2007·BMC Musculoskeletal Disorders·Jonathan AdachiWarren Cowell
Nov 13, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C T YeamJ J B Seng
Aug 2, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L ChouA E Wluka

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