Observations from a multicentre study on the use of the sputum specimen in patients hospitalized with community-acquired pneumonia.

The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses
E TaylorD Singer

Abstract

To describe the use of sputum Gram stain and culture in patients with community-acquired pneumonia (CAP) and to determine the factors that are associated with obtaining sputum for culture. Prospective observational cohort study of patients hospitalized for treatment of CAP at four medical institutions in three geographic locations. Results of Gram stain and culture of sputum; comparison of patients who had sputum processed for culture within 24 h of admission with those who did not have such a specimen processed during the first week of hospitalization; and the results of investigator assignment of etiology of pneumonia according to predefined criteria. Four hundred and seventy-eight of 1339 (36%) patients had a sputum specimen processed for culture within 24 h of admission. Patients who had a sputum specimen processed within 24 h of admission were more likely to be hospitalized at the Boston site (odds ratio [OR] 20.6) or Pittsburgh sites (3.4) and to have current sputum production, chronic obstructive lung disease and moderate or large amount of sputum. Female sex (0.4), neutropenia (0.05), and do not resuscitate status (0.36) were important predictors of failure to have a sputum processed for culture. The rate of Streptococc...Continue Reading

Citations

Jul 30, 2011·Chronic Respiratory Disease·Adam Malin

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