PMID: 43659Dec 1, 1979

Observations on long bone medullary pressures in relation to arterial PO2, PCO2 and pH in the anaesthetized dog

Acta Orthopaedica Scandinavica
E TøndevoldE Jansen

Abstract

To investigate the influence of variations in arterial oxygen tensions (PaO2), arterial carbon dioxide tensions (PaCO2), and arterial pH on long bone medullary pressures, seven anaesthetized dogs were investigated. Comparing the control medullary pressures, i.e. the mean medullary pressures obtained at the normal range of PaO2 (75--110 mmHg) with the mean medullary pressures corresponding to the range of PaO2 of less than 75 mmHg, statistically significant (P less than 0.05) decreases were seen in both epiphyseal, metaphyseal and diaphyseal medullary pressures, from 27.6 +/- 5.0 to 15.5 +/- 3.6 mmHg, from 23.5 +/- 2.9 to 13.9 +/- 2.3 mmHg and from 27.7 +/- 3.9 to 18.3 +/- 2.5 mmHg (all mean values +/- s.e. mean), respectively. Hyperoxia, hypocapnia, hypercapnia or metabolic acidosis had no effect on medullary pressures in any of the regions studied.

References

Feb 1, 1983·Acta Orthopaedica Scandinavica·E Tøndevold, J Bülow
Sep 29, 2009·Expert Opinion on Biological Therapy·Hyung-Min ChungJong-Hyuk Sung
Feb 7, 2015·Journal of Cellular Physiology·Mojca JežTuba Bas
Jan 19, 2010·The Journal of Surgical Research·Hamid AbdollahiPaul J DiMuzio
Apr 20, 2004·Journal of Cellular Physiology·Christopher L Murphy, Julia M Polak
Nov 1, 1993·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·T R Davis, M B Wood
Jan 23, 2009·Journal of Cellular Physiology·Zoran Ivanovic
Aug 27, 2005·Stem Cells·Francis HermitteZoran Ivanovic
Nov 18, 2005·American Journal of Physiology. Cell Physiology·Preeti MalladiMichael T Longaker
Aug 1, 1987·Acta Orthopaedica Scandinavica·H Kofoed, B Levander
Dec 27, 2011·Molecular and Cellular Biochemistry·Yating WangLingyong Jiang

Citations

Jun 1, 1968·The Journal of Bone and Joint Surgery. American Volume·S S Shim
Jan 1, 1968·Scandinavian Journal of Clinical and Laboratory Investigation·P Henningsen
May 1, 1959·The American Journal of Physiology·E HERZIG, W S ROOT
Jan 1, 1961·Medicina Experimentalis. International Journal of Experimental Medicine·B FOLKOWB LOFVING

Related Concepts

Arterial Blood pH Measurement
Dioxygen
Oxygen Measurement, Partial Pressure, Arterial
Regional Blood Flow
Hyperoxia
Entire Long Bone
Hypercapnia
Structure of Long Bone
Marrow
Hypocapnia

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