PMID: 589422Oct 1, 1977

Observations on syphilis in Addis Ababa. 2. Prevalence and natural history

The British Journal of Venereal Diseases
P S Friedman, D J Wright

Abstract

Sera from various groups were tested for syphilis by cardiolipin, fluorescent treponemal antibody-absorbed (FTA-ABS), and treponemal haemagglutination (TPHA) tests. The proportion of positive results, 12.7%, obtained from an unselected urban population suggested that the prevalence of the disease had declined since 1953. The probable explanation is the widespread use of penicillin. Late manifestations of syphilis are much rarer in Ethiopia than would be predicted from the high incidence at the infectious stage and, if present, they affect the cardiovascular system. These findings confirm old observations. Llymphocytes from Ethiopians with early syphilis did not proliferate when cultured with Treponema pallidum in vitro, in contrast with cells from patients with cardiovascular syphilis. These findings differed from observations made previously on patients in England with early syphilis.

References

Jul 1, 1975·Journal of the History of Medicine and Allied Sciences·R Pankhurst
Apr 1, 1967·Archives of Ophthalmology·L Z Cooper, S Krugman
May 1, 1974·Infection and Immunity·Z Reggiardo, G Middlebrook
Dec 1, 1972·The British Journal of Venereal Diseases·N A Johnston
Jan 1, 1974·Proceedings of the Society for Experimental Biology and Medicine·Z Reggiardo, G Middlebrook
Jun 1, 1973·The British Journal of Venereal Diseases·W F Felton
Jan 1, 1961·The Journal of Pathology and Bacteriology·C ISAACSON

Citations

Apr 1, 1981·The British Journal of Venereal Diseases·A O Osoba
Dec 1, 1982·The British Journal of Venereal Diseases·A V RatnamR C Mulenga
Oct 1, 1987·Genitourinary Medicine·H JamaS Bygdeman
Oct 1, 1988·Genitourinary Medicine·L F GuinnessA L Cornelis
Apr 1, 1990·Genitourinary Medicine·S O IsmailS Bygdeman
Jun 1, 1990·Genitourinary Medicine·S K HiraA Meheus
Dec 1, 1987·American Journal of Public Health·D M ParentiR H Hollenkamp
Jun 1, 1995·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·F JenniskensM Temmerman

Related Concepts

Diet
Delayed Hypersensitivity
Syphilis
Syphilis, Cardiovascular
Hutchinson's Teeth

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