PMID: 14405485Mar 1, 1960Paper

Observations on the effect of magnesium on blood coagulation

Journal of Clinical Pathology
R G HUNTSMANH LEHMANN

Abstract

Previous observations on the effect of oral magnesium and peptone on thrombin generation time are examined. The smallest amounts of magnesium and peptone regularly producing a significant shift demonstrable after one hour are 0.25 g. magnesium and 15 g. peptone. The oral effect can be reproduced by the intravenous injection of magnesium. The minimum amount required is 50 mg. The effect is transient, and after 30 minutes can no longer be demonstrated. Amounts of magnesium of the same order as those acting on intravenous injection can produce a shift of thrombin generation time in vitro. This action of magnesium in vitro can be antagonized by the addition of calcium.

References

Feb 1, 1953·Journal of Clinical Pathology·R G MACFARLANE, R BIGGS
Jul 25, 1959·Nature·M BETTEX-GALLAND, E F LUESCHER
Sep 1, 1942·The Biochemical Journal·H Lehmann, L Pollak

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Citations

Sep 1, 1988·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·S O Ayangade, O O Oyelola
Apr 27, 1963·British Medical Journal·H LEHMANN
Nov 1, 1968·Postgraduate Medical Journal·A E Buckle
Oct 5, 2016·Journal of Materials Science & Technology·Jun MaDonghui Zhu
Feb 17, 2015·Anaesthesia·H S NaS H Do
Feb 17, 2015·Anaesthesia·C Lyness, S V Mallett
Mar 19, 1960·Nature·R G HUNTSMANH LEHMANN
Oct 1, 1994·Alcoholism, Clinical and Experimental Research·L AbbottR K Rude
Nov 1, 1971·Klinische Wochenschrift·K Lossnitzer
Jan 1, 1967·Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie·M Walser
Jan 1, 1993·Progress in Cardiovascular Diseases·M A Arsenian
Nov 28, 2013·Pediatrics·Ran D GoldmanJeremy N Friedman

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