PMID: 11324381Apr 28, 2001Paper

Obsessive-compulsive disorders in adolescents with diagnosed schizophrenia

Psychiatria polska
J Rabe-Jabłońska

Abstract

The aim of the study was to assess the prevalence of OCD among 200 outpatients and inpatients (102 girls and 88 boys), 15-19 years old (mean age = 17.1 +/- 0.29) with schizophrenia (DSM-III-R, DSM-IV) and to determinate the time of onset of OCD: at least 6 months before schizophrenic symptoms, together with schizophrenic symptoms, while treatment with neuroleptics (name of drug, doses, duration of pharmacotherapy). Patients were examined with SCID-P for DSM-III-R and DSM-IV, version for patient, Y-BOCS and a specially prepared questionnaire for determining the age of onset, duration of OCD and a clinical picture of OCD. OCD was diagnosed in 13% adolescent patients with schizophrenia. Primary OCD--before schizophrenic symptoms was noted in 2.0% of patients, OCD together with schizophrenic symptoms in 4.5% of subjects, and while pharmacotherapy with various atypical neuroleptics: clozapine, risperidone, olanzapine in 6.0% of young patients. The most of assessed patients received clozapine (35 subjects), 24 subjects were treated with risperidone and 17 patients with olanzapine. It was determined that 14.3% of subjects used clozapine, 12.5% of subjects treated with risperidone and 5.9% treated with olanzapine presented OCD, where s...Continue Reading

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