Obstetric outcomes in pregnancy with pulmonary hypertension: A retrospective study of 78 cases at one center

The Journal of Obstetrics and Gynaecology Research
Cai-Xia ZhuZi-Lian Wang

Abstract

To identify the vary of obstetric outcomes by the severity of pulmonary hypertension (PH). A retrospective study involved pregnancies with PH in one certain academic institution. Total 78 pregnancies with PH were classified into three groups according the mean pulmonary arterial systolic pressure: mean pulmonary arterial systolic pressure 30-49 mm Hg (mild-PH group), mean pulmonary arterial systolic pressure 50-69 mm Hg (moderate-PH group) and mean pulmonary arterial systolic pressure ≥ 70 mm Hg (severe-PH group). The clinical features and obstetric outcomes were described and compared among three groups. The incidence of PH was 0.23%, including 57 cases in mild-PH group, 10 cases in moderate-PH group and 11 cases in severe-PH group. Meanwhile, pregnancies with mild PH present NYHA class I/II (P < 0.001). General anesthesia (P < 0.001) and advanced intensive care (P = 0.011) were supplied for pregnancies with severe PH. There was no significant difference in rate of caesarean delivery. Furthermore, severity of PH increased the risk of neonatal death (P = 0.040). The severity of PH seems to be a poor prognosis of neonatal death. Intensive care should be provided for pregnancies with severe PH.

References

Jan 17, 2009·European Heart Journal·Elisabeth BédardMichael A Gatzoulis
Dec 24, 2015·Pulmonary Circulation·Matthew MollHarrison W Farber
Jul 20, 2016·Journal of Natural Science, Biology, and Medicine·Sreyashi SenSudakshina Mukherji
Feb 9, 2017·Obstetrics and Gynecology·Marie-Louise MengElena Reitman
Mar 30, 2017·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Chew Kah TeikNor Azlin Mohamed Ismail

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