Obstetrics complications of systemic lupus erythematosus and antiphospholipid syndrome: A multidisciplinary management

Gynécologie, Obstétrique, Fertilité & Sénologie
A MattuizziL Sentilhes

Abstract

The main autoimmune diseases responsible for obstetric complications are systemic lupus erythematosus and antiphospholipid syndrome. They are particularly associated with an increased risk of miscarriage, stillbirth, intrauterine growth restriction, prematurity and pre-eclampsia. Therapeutics to prevent its complications are mainly low dose aspirin and low molecular weight heparins. However, the introduction of these therapies will have to consider the benefit/risk ratio to manage pregnancy and especially delivery. Consistency of care provided by autoimmunity specialists and gynaecologist-obstetricians is extremely important and must be promoted through regular exchanges, fuelled by a mutual culture, through multidisciplinary consultation meetings.

References

May 22, 2007·Lancet·Lisa M AskieUNKNOWN PARIS Collaborative Group
May 6, 2008·American Journal of Obstetrics and Gynecology·Megan E B ClowseAndra H James
Feb 13, 2009·Journal of Reproductive Immunology·Hideto YamadaHisanori Minakami
Aug 7, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Andrew SmythVesna D Garovic
Jun 12, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Edgardo AbalosLale Say
Jan 28, 2014·Annals of the Rheumatic Diseases·R CerveraUNKNOWN Euro-Phospholipid Project Group (European Forum on Antiphospholipid Antibodies)
Jan 27, 2015·Autoimmunity Reviews·Arsène MekinianUNKNOWN SNFMI and the European Forum on Antiphospholipid Antibodies
Jun 23, 2015·Annals of Internal Medicine·Jill P BuyonJane E Salmon
Oct 3, 2015·American Journal of Obstetrics and Gynecology·S SciasciaM J Cuadrado
Dec 25, 2015·British Journal of Clinical Pharmacology·Yusuf Cem KaplanGideon Koren
Oct 11, 2016·Lancet·Marc A RodgerUNKNOWN Low-Molecular-Weight Heparin for Placenta-Mediated Pregnancy Complications Study Group
Mar 22, 2019·BMJ : British Medical Journal·Maria C MagnusSiri E Håberg
Mar 31, 2019·Annals of the Rheumatic Diseases·Antonis FanouriakisDimitrios T Boumpas
May 17, 2019·Annals of the Rheumatic Diseases·Maria G TektonidouMichael M Ward

❮ Previous
Next ❯

Citations

Jun 3, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Elie NkwabongFelicité Nguefack Dongmo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.