Obstructive Sleep Apnea and Neurocognitive Dysfunction in Edentulous Patients

Journal of Prosthodontics : Official Journal of the American College of Prosthodontists
Soumyojeet BagchiJuhi Singh

Abstract

To record the incidence of cognitive dysfunction in edentulous patients suffering from obstructive sleep apnea (OSA) and establish a plausible hypothesis to explain the correlation of cognitive dysfunction and OSA. In this study, 315 edentulous patients (aged 60 to 65 years) visiting the outpatient department at Saraswati Dental College, Lucknow were recruited from January 2013 to October 2015. Prosthodontic Diagnostic Index (PDI) classification was used to assess the intraoral condition to relate it with the span of edentulousness. The BERLIN questionnaire and Epworth Sleepiness Scales were used to diagnose sleep-disordered breathing, following which the patients were put through all-night polysomnography. The apnea-hypopnea index (AHI) scores were derived. Mild and moderate OSA patients were classified into mild, moderate, and severe cognitive dysfunction based on SGRQ-C and SCD. Data were tabulated according to a new classification (Cognitive Dysfunction of Dental Sleep Medicine Patients [CDDSMP] Classification) designed specifically for this study. Data were analyzed using SPSS v15.0. Scores were tabulated as mean ± SD and median [IQR] values. Change from baseline was analyzed using Wilcoxon signed rank test. Mean scores at...Continue Reading

References

Dec 1, 1991·Sleep·S Ancoli-IsraelO Kaplan
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·H BearparkC Sullivan
Mar 1, 1994·American Journal of Respiratory and Critical Care Medicine·S RedlineV Ferrette
Jul 1, 1993·Journal of Internal Medicine·T GíslasonB Benediktsdóttir
Apr 29, 1993·The New England Journal of Medicine·T YoungS Badr
Aug 1, 1996·American Journal of Respiratory and Critical Care Medicine·K P Strohl, S Redline
Jan 28, 1998·American Journal of Respiratory and Critical Care Medicine·E O BixlerA Kales
May 11, 2000·The New England Journal of Medicine·P E PeppardJ Skatrud
Dec 21, 2000·JAMA : the Journal of the American Medical Association·P E PeppardJ Skatrud
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·E O BixlerA Kales
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·J DuránA Iztueta
Apr 23, 2002·Archives of Internal Medicine·Terry YoungUNKNOWN Sleep Heart Health Study Research Group
Oct 9, 2002·JAMA : the Journal of the American Medical Association·Katherine M FlegalClifford L Johnson
Sep 26, 1957·The New England Journal of Medicine·F K AUSTENR D ADAMS
Nov 8, 2003·American Journal of Respiratory and Critical Care Medicine·Zarir F UdwadiaChandrajeet I Singh
Dec 11, 2003·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·M T M AraújoB Fleury
Jun 3, 2004·American Journal of Respiratory and Critical Care Medicine·J Gabrielle BreugelmansNaresh M Punjabi
Sep 7, 2004·American Journal of Respiratory and Critical Care Medicine·JinKwan KimChol Shin
Sep 15, 2005·Journal of Applied Physiology·Terry YoungShahrad Taheri
Oct 18, 2005·Journal of Applied Physiology·Naresh M Punjabi, Vsevolod Y Polotsky
Jan 19, 2006·Respiratory Research·Caterina BuccaStefano Carossa
Jan 25, 2006·The American Journal of Medicine·Atul MalhotraDavid P White
Apr 28, 2006·The European Respiratory Journal·Y PekerJ Hedner
Jan 11, 2007·Sleep Medicine Reviews·V A BarvauxD O Rodenstein
Feb 6, 2007·Sleep Medicine Reviews·Sandrine H LaunoisPatrick Lévy
Mar 16, 2007·Obesity Surgery·Leandro Genehr FritscherJosé Miguel Chatkin
Apr 7, 2007·Chest·Matthias EikermannAtul Malhotra
Mar 4, 2009·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·David A Felton
Sep 16, 2015·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·David A Felton
Oct 1, 2015·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Arvind TripathiNarendra Gupta
Dec 24, 2015·Sleep Medicine Reviews·Melissa C LipfordRayleigh Ping-Ying Chiang

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