Obstructive sleep apnea and primary snoring in children with epilepsy.

Journal of Child Neurology
Sejal V JainTracy A Glauser

Abstract

Sleep-related breathing disruptions in children with epilepsy are common and can range from primary snoring to obstructive sleep apnea. Untreated obstructive sleep apnea can lead to significant morbidity. This study aimed to identify factors associated with its occurrence and severity in children with epilepsy. Children with epilepsy and sleep disruption were evaluated with polysomnography and diagnosed with obstructive sleep apnea or primary snoring. Statistical analyses were done to identify differences within both the groups and among the subjects in the obstructive sleep apnea group. Uncontrolled epilepsy was a risk factor for obstructive sleep apnea (80%) compared with primary snoring (47%, P = .02). Obstructive index increased with increasing number of antiepileptic drugs. In children with epilepsy and disturbed sleep, obstructive sleep apnea is associated with uncontrolled epilepsy and is more severe with polytherapy use. Children with uncontrolled seizures on antiepileptic polytherapy should be routinely screened for obstructive sleep apnea.

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Citations

Dec 3, 2014·Child and Adolescent Psychiatric Clinics of North America·Madeleine M Grigg-Damberger, Nancy Foldvary-Schaefer
Mar 25, 2014·Pediatric Neurology·Radhika DhamijaSuresh Kotagal
Mar 18, 2015·Pediatric Pulmonology·Kristie L DeHaanJoanna E MacLean
Nov 14, 2015·Current Problems in Pediatric and Adolescent Health Care·Sofia KonstantinopoulouRomy Hoque
Aug 12, 2014·Acta otorrinolaringológica española·Eduard Esteller
Nov 19, 2014·Sleep & Breathing = Schlaf & Atmung·Maria GogouEvaggelos Pavlou
Jul 12, 2016·Epilepsy Research·Maria GogouEvaggelos Pavlou
Nov 7, 2015·The European Respiratory Journal·Athanasios G KaditisStijn Verhulst
Oct 13, 2016·ERJ Open Research·Ramon FarréJosep M Montserrat
Nov 23, 2018·European Respiratory Review : an Official Journal of the European Respiratory Society·Angelica TiotiuAndras Bikov
Jan 22, 2019·British Journal of Clinical Pharmacology·Julie A StoneS Aubrey Stoch
Apr 27, 2017·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·X-Q ZhangY-J Lan
Nov 19, 2013·Current Opinion in Otolaryngology & Head and Neck Surgery·Norman R Friedman
Sep 30, 2018·Archives of Disease in Childhood·Frances Mary GibbonPaul Gringras
Mar 30, 2020·Molecular Genetics & Genomic Medicine·Jill M ArganbrightDavid G Ingram
Apr 1, 2020·Journal of Child Neurology·Sarah N GibbsEric Segal

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